SCHEMBL316485

SCHEMBL316485

C=C(C#N)C(=O)OCCCC(C)C

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 1/20 0.55
CYP19A1 P11511 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
ACHE P22303 1/20 0.31
BLM P54132 1/20 0.31
DNM1 Q05193 2/20 0.30
THRB P10828 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1924506 0.95 TSHR (0.53) TSHRALDH1A1CYP19A1TDP1ACHE
SCHEMBL21932806 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
SCHEMBL4621788 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
SCHEMBL15519654 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
SCHEMBL4578805 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
SCHEMBL5580248 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
SCHEMBL15520522 0.93 TSHR (0.51) TSHRALDH1A1CYP19A1TDP1DNM1
Isopentyl 2-Cyanoacrylate SCHEMBL450802 0.89 TSHR (0.58) TSHRALDH1A1CYP19A1TDP1ACHE
SCHEMBL20943619 0.87 TSHR (0.49) TSHRALDH1A1CYP19A1BLM
SCHEMBL4580407 0.83 TSHR (0.63) TSHRALDH1A1TDP1DNM1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026104704-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE FUNDACIÓ INSTITUT DE INVESTIGACIÓ EN CIÈNCIES DE LA SALUT GERMANS TRIAS I PUJOL (ES) 2026-05-21 WO claimed
EP-4744687-A1 A COMBINATION, MEDICAL KIT AND MEDICAL DEVICE FOR TREATING AND/OR PREVENTING TISSUE LEAKAGE Aesculap AG (DE) 2026-05-20 EP claimed
US-20250195443-A1 Polymer Nanoaggregate Pharmaceutical Composition and Use Thereof ANP TECHNOLOGIES, INC. (US) 2025-06-19 US claimed
US-20250108106-A1 NANOENCAPSULATED PHARMACEUTICAL COMPOSITION AND USE THEREOF FULGENT GENETICS, INC. 2025-04-03 US claimed
EP-4493219-A1 POLYMER NANOAGGREGATE PHARMACEUTICAL COMPOSITION AND USE THEREOF ANP Technologies, Inc. (US) 2025-01-22 EP claimed
CN-119233828-A Nano encapsulated pharmaceutical composition and use thereof 福君基因公司 2024-12-31 CN claimed
CN-119212725-A Polymer nano aggregate pharmaceutical composition and application thereof ANP科技公司 2024-12-27 CN claimed
US-20240151732-A1 EX VIVO METHOD FOR ANALYSING A TISSUE SAMPLE USING PROTEOMIC PROFILE MATCHING, AND ITS USE FOR THE DIAGNOSIS, PROGNOSIS OF PATHOLOGIES AND FOR PREDICTING RESPONSE TO TREATMENTS UNIVERSITÉ DE BORDEAUX (FR) 2024-05-09 US claimed
EP-4305424-A1 EX VIVO METHOD FOR ANALYSING A TISSUE SAMPLE USING PROTEOMIC PROFILE MATCHING, AND ITS USE FOR THE DIAGNOSIS, PROGNOSIS OF PATHOLOGIES AND FOR PREDICTING RESPONSE TO TREATMENTS UNIVERSITE DE BORDEAUX (FR) 2024-01-17 EP claimed
CN-117304818-A High-stability instant adhesive and preparation method thereof 东莞市国象胶粘制品有限公司 2023-12-29 CN claimed
US-8092819-B2 Implantable medical device coated with a bioactive agent Cook Medical Technologies LLC. (US) 2012-01-10 US claimed
EP-1993626-A2 IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT Med Institute, Inc. (US) 2008-11-26 EP claimed
US-20070207184-A1 Implantable medical device coated with a bioactive agent MED INSTITUTE, INC (US) 2007-09-06 US claimed
WO-2007089592-A2 IMPLANTABLE MEDICAL DEVICE COATED WITH BIOACTIVE AGENT MED INSTITUTE, INC. (US) 2007-08-09 WO claimed
US-20040028635-A1 Block-structure copolymer consisting of a saccharide segment bound to at least a biodegradable hydrophobic segment, and corresponding particles CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) (FR) 2004-02-12 US claimed
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH S.N. BIOTECH, INC. 2002-05-30 US claimed
EP-0824316-A4 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 2001-01-17 EP claimed
US-5767152-A USING A CYANOCARBOXYLIC ACID S.N. BIOTECH, INC. 1998-06-16 US claimed
EP-0824316-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH Nielsen, Thor, B. (US) 1998-02-25 EP claimed
WO-1996034526-A1 COMPOSITIONS AND METHODS FOR STIMULATING HAIR GROWTH NIELSEN THOR B (US) 1996-11-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020065314-A1 COMPOSITIONS AND METHOD FOR STIMULATING HAIR GROWTH AREG, NGF, HDGF TSHR 148/4885ALDH1A1 3677/4885CYP19A1 87/4885
US-20250195443-A1 Polymer Nanoaggregate Pharmaceutical Composition and Use Thereof BRCA1, TP53, PRNP TSHR 4578/4885ALDH1A1 4392/4885CYP19A1 3563/4885
US-20250108106-A1 NANOENCAPSULATED PHARMACEUTICAL COMPOSITION AND USE THEREOF STING1, CGAS, MAVS TSHR 4103/4885ALDH1A1 4767/4885CYP19A1 4076/4885
US-20040028635-A1 Block-structure copolymer consisting of a saccharide segment bound to at least a biodegradable hydrophobic segment, and corresponding particles MSR1, CBR1, GRHPR TSHR 972/4885ALDH1A1 956/4885CYP19A1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.