SCHEMBL450829

SCHEMBL450829

O=C(O)c1ccc(OCOc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.67
NR4A2 P43354 3/20 0.62
NR4A1 P22736 1/20 0.62
NR4A3 Q92570 1/20 0.62
TP53 P04637 2/20 0.58
TSHR P16473 2/20 0.58
PLA2G4B P0C869 2/20 0.58
MAPK1 P28482 1/20 0.58
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
RXRA P19793 3/20 0.56
RXRB P28702 3/20 0.56
SRD5A2 P31213 1/20 0.56
NPC1 O15118 1/20 0.56
POLB P06746 1/20 0.56
RAB9A P51151 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ALDH1A1 P00352 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8123793 0.87 CA1 (0.61) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL155030 0.87 CA1 (0.61) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL196110 0.86 PKM (0.88) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL12940638 0.86 PLA2G4B (0.64) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL118037 0.84 PKM (0.77) PKMTP53TSHRPLA2G4BMAPK1
SCHEMBL1952122 0.84 TP53 (0.79) PKMTP53TSHRPLA2G4BMAPK1
SCHEMBL5914350 0.84 PKM (0.64) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL18319953 0.82 CA1 (0.55) PKMNR4A2NR4A1NR4A3TP53
SCHEMBL2181009 0.82 TP53 (0.82) PKMTP53TSHRPLA2G4BPOLB
SCHEMBL2180731 0.82 TP53 (0.82) PKMTP53TSHRPLA2G4BPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4242257-B1 POLYMER-CLAY COMPOSITE AND ORGANOCLAY UNIV SOUTHAMPTON (GB) 2025-07-02 EP claimed
EP-4493149-A2 METHODS FOR MARKING A TARGET LOCATION FOR A MEDICAL PROCEDURE Ephemeral Solutions, Inc. (US) 2025-01-22 EP claimed
US-20250009843-A1 COMPOSITIONS AND METHODS FOR TREATMENTS BY MODULATION OF EXCITABLE TISSUES ACTIVITIES, AND FOR ANTIMICROBIAL APPLICATIONS NAT UNIVESITY OF IRELAND GALWAY (IE) 2025-01-09 US claimed
US-20240350707-A1 TISSUE SCAFFOLD AND SCAFFOLD COMPOSITION LOCATE BIO LIMITED (GB) 2024-10-24 US claimed
WO-2024211384-A1 EGG BASED MICROCARRIERS AND SCAFFOLDS FOR CELLULAR AGRICULTURE AND OTHER APPLICATIONS HATCHLESS INC. (US) 2024-10-10 WO claimed
US-11904070-B2 Tissue scaffold and scaffold composition LOCATE THEAPEUTICS LIMITED (GB) 2024-02-20 US claimed
EP-4291136-A1 PARTICLES CONTAINING COLORING AGENTS AND METHODS OF USING THE SAME Ephemeral Solutions, Inc. (US) 2023-12-20 EP claimed
US-20230398058-A1 PARTICLES CONTAINING COLORING AGENTS AND METHODS OF USING THE SAME EPHEMERAL SOLUTIONS, INC. 2023-12-14 US claimed
WO-2023178213-A2 METHODS FOR MARKING A TARGET LOCATION FOR A MEDICAL PROCEDURE EPHEMERAL SOLUTIONS, INC. (US) 2023-09-21 WO claimed
EP-4242257-A1 POLYMER-CLAY COMPOSITE AND ORGANOCLAY University Of Southampton (GB) 2023-09-13 EP claimed
US-5902599-A PHOTOPOLYMERIZING ANHYDRIDE MONOMERS OR OLIGOMERS HAVING UNSATURATION FOR CROSSLINKING; POLYANHYDRIDES HAVING GOOD PROCESSIBILITY, STRENGTH AND MECHANICAL PROPERTIES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1999-05-11 US claimed
EP-0912166-A1 METHODS AND COMPOSITIONS FOR ENHANCING THE BIOADHESIVE PROPERTIES OF POLYMERS USING ORGANIC EXCIPIENTS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1999-05-06 EP claimed
WO-1997049385-A1 METHODS AND COMPOSITIONS FOR ENHANCING THE BIOADHESIVE PROPERTIES OF POLYMERS USING ORGANIC EXCIPIENTS BROWN UNIVERSITY RESEARCH FOUNDATION (US) 1997-12-31 WO claimed
EP-0746342-A1 BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM FUISZ TECHNOLOGIES LTD. (US) 1996-12-11 EP claimed
EP-0568651-A4 BIODEGRADABLE POLYMER BLENDS FOR DRUG DELIVERY NOVA PHARM CORP (US) 1996-11-27 EP claimed
US-5518730-A Biodegradable controlled release flash flow melt-spun delivery system FUISZ TECHNOLOGIES LTD. (US) 1996-05-21 US claimed
EP-0746342-A4 BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM FUISZ TECHNOLOGIES LTD (US) 1996-01-11 EP claimed
WO-1993024154-A1 BIODEGRADABLE CONTROLLED RELEASE MELT-SPUN DELIVERY SYSTEM FUISZ TECHNOLOGIES, LTD. (US) 1993-12-09 WO claimed
EP-0568651-A1 BIODEGRADABLE POLYMER BLENDS FOR DRUG DELIVERY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1993-11-10 EP claimed
WO-1992013567-A1 BIODEGRADABLE POLYMER BLENDS FOR DRUG DELIVERY NOVA PHARMACEUTICAL CORPORATION (US) 1992-08-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230398058-A1 PARTICLES CONTAINING COLORING AGENTS AND METHODS OF USING THE SAME LDHA, CUTA, LIPA PKM 1284/4885NR4A2 3741/4885NR4A1 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.