Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8123793 | 0.94 | CA1 (0.61) | CA1CA2NPC1POLBRAB9A | |
| SCHEMBL155030 | 0.94 | CA1 (0.61) | CA1CA2NPC1POLBRAB9A | |
| SCHEMBL12926337 | 0.83 | MAPT (0.50) | PARP10NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL450829 | 0.82 | PKM (0.67) | CA1CA2NPC1POLBRAB9A | |
| SCHEMBL12926336 | 0.82 | MMP2 (0.51) | TSHR | |
| SCHEMBL9549256 | 0.81 | KMT2A (0.53) | PARP10RAB9ASMN1; SMN2SRD5A2MAPK1 | |
| SCHEMBL3798190 | 0.81 | CES2 (0.59) | PARP10NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL1503531 | 0.81 | PKM (0.56) | CA1CA2NPC1POLBRAB9A | |
| Ethane SCHEMBL11219716 | 0.80 | PARP10 (0.72) | CA1CA2PARP15PARP10RAB9A | |
| SCHEMBL22281 | 0.80 | PARP10 (0.78) | CA1CA2PARP15PARP10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112343-B1 | AMIDE DERIVATIVES | UNIV TOHOKU (JP) | 2023-03-29 | — | — | EP | disclosed |
| US-11040937-B2 | Amide derivative | TOHOKU UNIVERSITY (JP) | 2021-06-22 | — | — | US | disclosed |
| EP-3112343-A1 | AMIDE DERIVATIVES | Tohoku University (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20160368860-A1 | AMIDE DERIVATIVE | TOHOKU UNIVERSITY (JP) | 2016-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160368860-A1 | AMIDE DERIVATIVE | ARG1, PTMS, MLX | CA1 1294/4885CA2 1487/4885PARP15 3415/4885 |
| US-11040937-B2 | Amide derivative | ARG1, PTMS, MLX | CA1 1294/4885CA2 1487/4885PARP15 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.