Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 3/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508465 | 1.00 | RAB9A (0.48) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4508463 | 1.00 | RAB9A (0.48) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4518006 | 0.90 | RAB9A (0.51) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4517999 | 0.90 | RAB9A (0.51) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4518007 | 0.90 | RAB9A (0.51) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4507125 | 0.87 | RAB9A (0.49) | RAB9AALDH1A1NPC1USP2TP53 | |
| SCHEMBL4507132 | 0.87 | RAB9A (0.49) | RAB9AALDH1A1NPC1USP2TP53 | |
| SCHEMBL4507130 | 0.87 | RAB9A (0.49) | RAB9AALDH1A1NPC1USP2TP53 | |
| SCHEMBL4503150 | 0.80 | ALDH1A1 (0.56) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 | |
| SCHEMBL4503157 | 0.80 | ALDH1A1 (0.56) | RAB9ATPSAB1TPSD1TPSG1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | RAB9A 4698/4885TPSAB1 60/4885TPSD1 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.