SCHEMBL4508940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13674540	1.00	HSD11B1 (0.37)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL4528144	0.91	ACVRL1 (0.38)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL13674541	0.91	ACVRL1 (0.38)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL4517259	0.90	HSD11B1 (0.40)	HSD11B1ACVRL1ACVR1BMPR1BBMPR1A
	SCHEMBL13674534	0.90	HSD11B1 (0.40)	HSD11B1ACVRL1ACVR1BMPR1BBMPR1A
	SCHEMBL13675620	0.89	HSD11B1 (0.39)	HSD11B1MCHR1PGRDPP4DPP8
	SCHEMBL13674536	0.89	HRH3 (0.39)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL13674532	0.89	MCHR1 (0.39)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL5543774	0.89	HRH3 (0.39)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B
	SCHEMBL4518383	0.89	MCHR1 (0.39)	HSD11B1MCHR1ACVRL1ACVR1BMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.