Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499629 | 0.88 | SGMS2 (0.56) | KMT2APOLBTAAR1SCDCHRNB2 | |
| SCHEMBL183867 | 0.72 | ATP4A (0.51) | KMT2AMAPTMAPK1MEN1 | |
| SCHEMBL4516495 | 0.71 | KMT2A (0.73) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL2664613 | 0.70 | LRRK2 (0.62) | KMT2ALRRK2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL4868622 | 0.69 | KMT2A (0.74) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL12615802 | 0.69 | GCK (0.67) | KMT2ALRRK2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL45148 | 0.69 | KMT2A (0.73) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL21931945 | 0.68 | KMT2A (0.63) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL30533391 | 0.68 | KMT2A (0.71) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL29238994 | 0.68 | KMT2A (0.71) | KMT2ACHRNB2CHRNB4CHRNA3CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | KMT2A 1109/4885LRRK2 949/4885POLB 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.