Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 16/20 | 0.45 |
| ▸ | PLK1 | P53350 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4188323 | 0.86 | BACE1 (0.39) | MEN1LMNAKMT2ANPSR1 | |
| SCHEMBL4510042 | 0.82 | CRHR1 (0.50) | CRHR1 | |
| SCHEMBL27794965 | 0.80 | CRHR1 (0.37) | CRHR1MEN1LMNAKMT2A | |
| SCHEMBL11947609 | 0.80 | L3MBTL1 (0.40) | CRHR1MEN1TSHRMAPK1KMT2A | |
| SCHEMBL4346798 | 0.80 | L3MBTL1 (0.40) | CRHR1MEN1TSHRMAPK1KMT2A | |
| SCHEMBL4346805 | 0.80 | L3MBTL1 (0.40) | CRHR1MEN1TSHRMAPK1KMT2A | |
| SCHEMBL4496282 | 0.79 | ALDH1A1 (0.46) | CRHR1PLK1MEN1NR1I2GMNN | |
| SCHEMBL4497783 | 0.76 | TACR1 (0.40) | CRHR1PLK1 | |
| SCHEMBL4509471 | 0.74 | AR (0.39) | CRHR1PLK1 | |
| SCHEMBL4495188 | 0.73 | CRHR1 (0.46) | CRHR1PLK1MEN1NR1I2GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023729-A1 | Trisubstituted amine compound | CETP, MTTP, APOB | CRHR1 3834/4885PLK1 4219/4885MEN1 2338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.