Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4498562 | 0.91 | EPHA2 (0.44) | PDK1EPHA2KDREPHB4GRM5 | |
| SCHEMBL4509367 | 0.89 | MEN1 (0.51) | PDK1MAPTNPC1RAB9AKMT2A | |
| SCHEMBL4500338 | 0.89 | PDK1 (0.46) | PDK1MAPTNPC1RAB9AGRM5 | |
| SCHEMBL4490668 | 0.81 | EPHA2 (0.43) | PDK1EPHA2KDREPHB4DRD4 | |
| SCHEMBL4516917 | 0.81 | EPHA2 (0.44) | MAPTKMT2AEPHA2KDREPHB4 | |
| SCHEMBL4507600 | 0.80 | PDK1 (0.42) | PDK1EPHA2KDREPHB4DRD4 | |
| SCHEMBL4505525 | 0.80 | EPHA2 (0.45) | EPHA2KDREPHB4GRM5DRD4 | |
| Trifluoroacetic Acid SCHEMBL4518310 | 0.80 | PHGDH (0.40) | PDK1MAPTKMT2AEPHA2KDR | |
| SCHEMBL4506372 | 0.79 | TRPV1 (0.43) | PDK1MAPTKMT2AGRM5DRD4 | |
| Hydrochloric Acid SCHEMBL4492473 | 0.78 | PDK1 (0.41) | PDK1EPHA2KDREPHB4DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | PDK1 663/4885MAPT 4022/4885NPC1 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.