Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506372 | 0.89 | TRPV1 (0.43) | PDK1MAPTFKBP1ACCR3DRD4 | |
| SCHEMBL4510657 | 0.89 | PDK1 (0.46) | PDK1NPC1RAB9AMAPTDRD4 | |
| SCHEMBL4498562 | 0.88 | EPHA2 (0.44) | PDK1OPRM1CCR3DRD4GRM5 | |
| Trifluoroacetic Acid SCHEMBL4495237 | 0.85 | TRPV1 (0.40) | PDK1CCR3DRD4NR1H4GRM5 | |
| SCHEMBL4509367 | 0.79 | MEN1 (0.51) | PDK1NPC1RAB9AMAPTDRD4 | |
| SCHEMBL4496536 | 0.78 | RBP4 (0.46) | PDK1 | |
| Trifluoroacetic Acid SCHEMBL4516194 | 0.78 | GRM5 (0.40) | PDK1CCR3DRD4TSHRGRM5 | |
| SCHEMBL4490668 | 0.78 | EPHA2 (0.43) | PDK1CCR3DRD4 | |
| SCHEMBL4516917 | 0.77 | EPHA2 (0.44) | MAPTDRD4GRM5 | |
| SCHEMBL4507600 | 0.77 | PDK1 (0.42) | PDK1CCR3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | PDK1 663/4885NPC1 57/4885RAB9A 3368/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.