Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 6/20 | 0.65 |
| ▸ | TNKS | O95271 | 7/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 7/20 | 0.49 |
| ▸ | WNT3A | P56704 | 2/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5611707 | 0.87 | DHFR (0.70) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL1689041 | 0.86 | DHFR (0.60) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL1689321 | 0.83 | DHFR (0.65) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL1688958 | 0.83 | DHFR (0.65) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL5611463 | 0.82 | DHFR (0.64) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL5611631 | 0.82 | DHFR (0.66) | DHFRTNKSTNKS2CYP1A1CYP1B1 | |
| SCHEMBL1689319 | 0.82 | DHFR (0.62) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL5611867 | 0.80 | DHFR (0.62) | DHFRTNKSTNKS2PARP2CYP1A1 | |
| SCHEMBL1689008 | 0.78 | DHFR (0.46) | DHFRTNKSTNKS2WNT3AALDH1A1 | |
| SCHEMBL5611811 | 0.77 | DHFR (0.61) | DHFRALDH1A1LMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247517-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | IRM LLC (BM) | 2009-10-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247517-A1 | COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY | CNR1, CNR2, FAAH | DHFR 2867/4885TNKS 932/4885TNKS2 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.