SCHEMBL451129

SCHEMBL451129

COC(OC)c1ccccc1[SiH3]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
ACHE P22303 1/20 0.32
CA4 P22748 2/20 0.32
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
CA9 Q16790 1/20 0.32
CA14 Q9ULX7 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAP2K7 O14733 1/20 0.31
GMNN O75496 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8853406 0.89
SCHEMBL17864869 0.84 ESR1 (0.40) ESR1CA1CA2SLC6A2SLC6A4
SCHEMBL6258936 0.77 MAPT (0.48) ESR1CA1CA2SLC6A2SLC6A4
SCHEMBL23630903 0.76 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL2354738 0.75 GABRA1 (0.46) ESR1CA1CA2SLC6A2ACHE
SCHEMBL3206497 0.75 ESR1 (0.56) ESR1CA1CA2SLC6A2SLC6A4
SCHEMBL1918798 0.75 CA1 (0.57) CA1CA2ACHECA4CA12
SCHEMBL699772 0.75 ALDH1A1 (0.38) ACHEALDH1A1TP53CYP1A2CYP3A4
SCHEMBL3378475 0.74 GABRA1 (0.50) CA1CA2SLC6A2CA12CA9
SCHEMBL3213376 0.73 ESR1 (0.33) ESR1CA1CA2SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 755 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122095037-A Coating composition 2026-05-26 CN claimed
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE MEGA P&C ADVANCED MAT SHANGHAI CO LTD (CN) 2026-04-30 US claimed
EP-4653505-A1 COATING COMPOSITION, MATERIAL PRODUCT THEREOF, KIT, AND USE METHOD Mega P&C Advanced Materials (Shanghai) Co., Ltd. (CN) 2025-11-26 EP claimed
WO-2025040760-A1 COATING COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2025-02-27 WO claimed
CN-119505368-A Hydrophobic composite material, preparation method thereof and application thereof in 3D printing silicon rubber 中国科学院理化技术研究所 2025-02-25 CN claimed
US-11904352-B2 Low dielectric constant film and preparation method thereof JIANGSU FAVORED NANOTECHNOLOGY CO., LTD. (CN) 2024-02-20 US claimed
CN-115521502-B Modified white carbon black micron aggregate and preparation method and application thereof 济南优纳泰克新材料科技有限公司 2024-01-26 CN claimed
CN-109073974-B Low-temperature curable negative photosensitive composition 默克专利有限公司 2023-09-01 CN claimed
US-11655118-B2 Film roll and film bundle TOYOBO CO., LTD. (JP) 2023-05-23 US claimed
EP-3253807-B1 PROCESS FOR PRODUCING POLYETHYLENE BOREALIS AG (AT) 2023-04-26 EP claimed
EP-2276872-A1 DEVICE FOR THERMOHYDRAULIC APPLICATIONS WITH IMPROVED WATER SOFTENING PROPERTIES, LOWER RELEASE OF HEAVY METALS, AND RELATIVE METHOD OF MANUFACTURING Moma S.r.l. (IT) 2011-01-26 EP claimed
WO-2009130288-A1 DEVICE FOR THERMOHYDRAULIC APPLICATIONS WITH IMPROVED WATER SOFTENING PROPERTIES, LOWER RELEASE OF HEAVY METALS, AND RELATIVE METHOD OF MANUFACTURING MOMA S.R.L. (IT) 2009-10-29 WO claimed
US-20090123647-A1 TRANSPARENT AQUA-BASED NANO SOL-GEL COMPOSITION AND METHOD OF APPLYING THE SAME ONID TECHNOLOGY (SHANGHAI) CORP. (CN) 2009-05-14 US claimed
US-7045568-B2 Aqueous dispersion type pressure-sensitive adhesive composition, and pressure-sensitive adhesive sheet NITTO DENKO CORPORATION (JP) 2006-05-16 US claimed
US-20050038152-A1 Aqueous dispersion type pressure-sensitive adhesive composition, and pressure-sensitive adhesive sheet NITTO DENKO CORPORATION 2005-02-17 US claimed
US-6713207-B2 Membrane electrode assembly, and solid polymer fuel cell using the assembly KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2004-03-30 US claimed
EP-0854891-B1 PROCESS FOR PREPARING COATED PLASTIC SURFACES DOW GLOBAL TECHNOLOGIES INC (US) 2003-05-28 EP claimed
WO-2003031362-A1 COATED GLASS FOR USE IN DISPLAYS AND OTHER ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES INC. (US) 2003-04-17 WO claimed
US-20020001744-A1 Membrane electrode assembly, and solid polymer fuel cell using the assembly KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2002-01-03 US claimed
US-5718967-A PLASMA POLYMERIZED ORGANOSILICON COMPOUNDS; LIQUID CRYSTAL DISPLAY DEVICES THE DOW CHEMICAL COMPANY (US) 1998-02-17 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260117072-A1 COATING COMPOSITION AND ITS COATED MATERIAL PRODUCTS, KITS, AND METHODS OF USE ILK, BMI1, C9 ESR1 1493/4885CA1 6/4885CA2 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.