Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.36 |
| ▸ | PPARA | Q07869 | 9/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12500584 | 0.88 | KDM4E (0.42) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL8526433 | 0.81 | PPARG (0.38) | PPARGPPARAGAAHPGDHSD17B10 | |
| SCHEMBL4905650 | 0.75 | KDM4E (0.38) | PPARGPPARAKDM4EALDH1A1GAA | |
| SCHEMBL4013345 | 0.72 | KDM4E (0.39) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL10399945 | 0.72 | SMN1; SMN2 (0.45) | KDM4EMEN1KMT2AHIF1AMAPT | |
| SCHEMBL2786997 | 0.68 | KMT2A (0.40) | KDM4EALDH1A1GAAMEN1KMT2A | |
| SCHEMBL1871593 | 0.67 | TSHR (0.54) | ALDH1A1HPGDHSD17B10CYP1A2CYP2C19 | |
| SCHEMBL8075767 | 0.67 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAHPGDHSD17B10 | |
| SCHEMBL21195781 | 0.66 | SLC1A1 (0.49) | PPARGPPARAKDM4EALDH1A1CYP1A2 | |
| SCHEMBL5822045 | 0.65 | LMNA (0.35) | PPARGPPARAALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140295403-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-10-02 | — | — | US | disclosed |
| US-8632966-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2014-01-21 | — | — | US | disclosed |
| US-20130217041-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-08-22 | — | — | US | disclosed |
| US-8377686-B2 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2013-02-19 | — | — | US | disclosed |
| US-20090117600-A1 | Detection of biological molecules by differential partitioning of enzyme substrates and products | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2009-05-07 | — | — | US | disclosed |
| US-7402426-B2 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2008-07-22 | — | — | US | disclosed |
| EP-1539986-B1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | UNIV KINGSTON (CA) | 2007-07-18 | — | — | EP | disclosed |
| EP-1539986-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | Queen's University at Kingston (CA) | 2005-06-15 | — | — | EP | disclosed |
| US-20040106164-A1 | Analyzing microorganism associated with an enzyme in a sample water, food, soil, or a biological sample, enzyme-linked immunosorbent assay, automatic detect fluorescence with optical fiber, separate with polydimethylsiloxane films; diagnostic kits | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-06-03 | — | — | US | disclosed |
| WO-2004027084-A1 | DETECTION OF BIOLOGICAL MOLECULES BY DIFFERENTIAL PARTITIONING OF ENZYME SUBSTRATES AND PRODUCTS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2004-04-01 | — | — | WO | disclosed |