SCHEMBL5822045

SCHEMBL5822045

O=C[C@H](Oc1ccccc1)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
MTNR1A P48039 1/20 0.33
MTNR1B P49286 1/20 0.33
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
PPARG P37231 6/20 0.33
PPARA Q07869 6/20 0.33
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
RECQL P46063 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1377219 1.00 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1MTNR1A
SCHEMBL3512233 1.00 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1MTNR1A
SCHEMBL7913872 0.86 APP (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL9191589 0.86 APP (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL8593832 0.86 LMNA (0.34) LMNAL3MBTL1PDE4ATDP1
SCHEMBL707743 0.80 MEN1 (0.42) LMNATDP1MAPTALDH1A1
SCHEMBL8603750 0.80 MEN1 (0.42) LMNATDP1MAPTALDH1A1
SCHEMBL1582160 0.80 MEN1 (0.42) LMNATDP1MAPTALDH1A1
SCHEMBL9634744 0.80 MEN1 (0.42) LMNATDP1MAPTALDH1A1
SCHEMBL7755252 0.79 EPHX1 (0.32) LMNAL3MBTL1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-60133853-A None JP disclosed
JP-7308171-A None JP disclosed
JP-7330574-A None JP disclosed
JP-2006028020-A COSMETIC COMPOSITION COMPRISING COLLAGEN AND RAW SUGAR EXTRACT OSAKA YAKUHIN KENKYUSHO:KK 2006-02-02 JP disclosed
US-5750362-A Methods for identifying substances with a potential herbicidal or growth-regulating action by means of plant transporter proteins, the use of the transporter proteins, and substances with a herbicidal and growth-regulating action BASF AKTIENGESELLSCHAFT (DE) 1998-05-12 US disclosed
JP-H07330574-A COSMETIC COMPOSITION OSAKA YAKUHIN KENKYUSHO:KK 1995-12-19 JP disclosed
JP-H07308171-A ANTIALLERGIC FOOD OSAKA YAKUHIN KENKYUSHO:KK 1995-11-28 JP disclosed
JP-S60133853-A HEALTH FOOD OSAKA CHEM LAB 1985-07-17 JP disclosed