Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | LYN | P07948 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | ROS1 | P08922 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508842 | 0.85 | ALDH1A1 (0.52) | SCD5ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL4499452 | 0.85 | SCD5 (0.43) | SCD5ALDH1A1MRGPRX4CYP2C8CYP2B6 | |
| SCHEMBL4506513 | 0.84 | SCD5 (0.49) | SCD5ALDH1A1MRGPRX4CYP2C8CYP2B6 | |
| SCHEMBL4508856 | 0.83 | MRGPRX4 (0.48) | SCD5ALDH1A1KDRMRGPRX4MAOB | |
| SCHEMBL4507951 | 0.82 | SCD (0.49) | SCD5ALDH1A1KDRMRGPRX4MAOB | |
| Trifluoroacetic Acid SCHEMBL4504473 | 0.81 | ALDH1A1 (0.46) | SCD5ALDH1A1MRGPRX4JAK2TYK2 | |
| SCHEMBL4505841 | 0.79 | MEN1 (0.43) | ALDH1A1MRGPRX4JAK2TYK2CYP2C9 | |
| SCHEMBL4496601 | 0.79 | MAPT (0.60) | ALDH1A1KDRMRGPRX4MAOBPLK4 | |
| Hydrochloric Acid SCHEMBL4496489 | 0.77 | MRGPRX4 (0.47) | ALDH1A1KDRMRGPRX4MAOBPLK4 | |
| SCHEMBL4508426 | 0.75 | ALDH1A1 (0.56) | SCD5ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | SCD5 2/4885ALDH1A1 1311/4885KDR 618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.