Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 7/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2996004 | 0.90 | P2RX7 (0.43) | HSD11B1P2RX7EPHX2FFAR1 | |
| SCHEMBL2992277 | 0.90 | P2RX7 (0.43) | HSD11B1P2RX7EPHX2FFAR1 | |
| SCHEMBL4512444 | 0.87 | HSD11B1 (0.54) | HSD11B1CYP26A1P2RX7ESR1ESR2 | |
| SCHEMBL4513997 | 0.86 | HSD11B1 (0.41) | HSD11B1CYP26A1P2RX7ESR1ESR2 | |
| SCHEMBL4513605 | 0.86 | FFAR4 (0.40) | HSD11B1 | |
| SCHEMBL14365228 | 0.83 | HSD11B1 (0.39) | HSD11B1CYP26A1P2RX7ESR1ESR2 | |
| SCHEMBL4502408 | 0.82 | HSD11B1 (0.39) | HSD11B1CYP26A1P2RX7ESR1ESR2 | |
| SCHEMBL4515447 | 0.82 | S1PR1 (0.39) | HSD11B1FFAR1 | |
| SCHEMBL4508780 | 0.81 | HSD11B1 (0.37) | HSD11B1P2RX7ESR1 | |
| SCHEMBL4508921 | 0.81 | HSD11B1 (0.42) | HSD11B1CYP2C9ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | HSD11B1 1/4885CYP26A1 66/4885P2RX7 3946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.