Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | PRKX | P51817 | 1/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504216 | 0.91 | HSD11B1 (0.47) | S1PR1S1PR5PRKXACVR1MAOA | |
| SCHEMBL14365300 | 0.87 | MAOB (0.39) | S1PR1S1PR5PRKXACVR1MAOA | |
| SCHEMBL4508467 | 0.86 | S1PR1 (0.37) | S1PR1S1PR5PRKXACVR1MAOA | |
| SCHEMBL4510560 | 0.85 | HSD11B1 (0.41) | S1PR1S1PR5PRKXACVR1MAOA | |
| SCHEMBL4513743 | 0.83 | GRM5 (0.36) | MAOAMAOBHSD11B1FFAR1 | |
| SCHEMBL4512383 | 0.82 | HSD11B1 (0.40) | HSD11B1FFAR1 | |
| SCHEMBL2996004 | 0.81 | P2RX7 (0.43) | HSD11B1FFAR1 | |
| SCHEMBL2992277 | 0.81 | P2RX7 (0.43) | HSD11B1FFAR1 | |
| SCHEMBL4519338 | 0.81 | HSD11B1 (0.60) | S1PR1S1PR5PRKXACVR1MAOA | |
| SCHEMBL4500417 | 0.81 | HSD11B1 (0.47) | S1PR1S1PR5PRKXACVR1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | S1PR1 521/4885S1PR5 823/4885PRKX 3496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.