SCHEMBL451263

SCHEMBL451263

C=C(C)C(=O)OCc1ccc(Br)cc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.50
MAPT P10636 3/20 0.50
KMT2A Q03164 3/20 0.50
MEN1 O00255 1/20 0.50
ALDH1A1 P00352 3/20 0.49
HPGD P15428 1/20 0.49
MAOB P27338 5/20 0.49
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
MAOA P21397 3/20 0.44
MMP1 P03956 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
RXRA P19793 1/20 0.42
RXRB P28702 1/20 0.42
IDO1 P14902 1/20 0.42
FABP7 O15540 1/20 0.42
FABP5 Q01469 1/20 0.42
THRB P10828 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL254038 0.91 ALDH1A1 (0.50) KMT2AMEN1ALDH1A1HTTTDP1
SCHEMBL92326 0.85 MEN1 (0.53) KDM4EKMT2AMEN1ALDH1A1HTT
SCHEMBL15944747 0.85 ALDH1A1 (0.46) KDM4EKMT2AMEN1ALDH1A1HTT
SCHEMBL16125663 0.85 ALDH1A1 (0.46) MAPTKMT2AMEN1ALDH1A1HTT
SCHEMBL17791311 0.85 ALDH1A1 (0.46) KDM4EKMT2AMEN1ALDH1A1HTT
SCHEMBL24019226 0.85 ALDH1A1 (0.46) MAPTKMT2AMEN1ALDH1A1HTT
SCHEMBL10720993 0.84 ALDH1A1 (0.44) KDM4EMAPTKMT2AMEN1ALDH1A1
SCHEMBL4354853 0.84 ALDH1A1 (0.44) KDM4EKMT2AMEN1ALDH1A1HPGD
SCHEMBL9554958 0.84 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1HTTTDP1
SCHEMBL148297 0.84 MAOB (0.47) MAPTALDH1A1MAOBMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2355 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024148654-A1 OPHTHALMIC COMPOSITION CONTAINING VVN539, AND USE THEREOF 维眸生物科技(浙江)有限公司 2024-07-18 WO claimed
CN-118340775-A Ophthalmic composition containing VVN539 and application thereof 维眸生物科技(浙江)有限公司 2024-07-16 CN claimed
CN-118165606-B Preparation method of polylactic acid type full-degradable water-based gloss oil 上海高邦印刷材料有限公司 2024-07-05 CN claimed
CN-118221129-A Hierarchical pore SBA-15 molecular sieve and preparation method thereof 中国石油天然气股份有限公司 2024-06-21 CN claimed
CN-115724419-B Method for preparing hollow carbon sphere by one-pot method and application 中国科学院大连化学物理研究所 2024-06-18 CN claimed
CN-118005175-B Fracturing flowback fluid treatment method and device for high-alkalinity oil field 克拉玛依市三达新技术股份有限公司 2024-06-18 CN claimed
CN-118206705-A Raspberry-shaped phenolic resin or carbon/molybdenum disulfide composite material, preparation and application 中国石油化工股份有限公司 2024-06-18 CN claimed
CN-118185028-A Polyvinylamine-based multiblock polymer for nucleic acid drug delivery 福建医科大学 2024-06-14 CN claimed
CN-118165606-A Preparation method of polylactic acid type full-degradable water-based gloss oil 上海高邦印刷材料有限公司 2024-06-11 CN claimed
CN-118083952-A Preparation method of biomass-based sodium ion battery negative hard carbon material 中国科学技术大学 2024-05-28 CN claimed
WO-1997002022-A1 BIOCOMPATIBLE AND BIODEGRADABLE NANOPARTICLES DESIGNED FOR PROTEINACEOUS DRUGS ABSORPTION AND DELIVERY EUROPEAN COMMUNITY (LU) 1997-01-23 WO claimed
EP-0752245-A1 Biocompatible and biodegradable nanoparticles designed for proteinaceous drugs absorption and delivery UNIVERSITY OF LIEGE (BE) 1997-01-08 EP claimed
EP-0554427-B1 REFERENCE HALF-CELL ELECTRODE KODAK PATHE (FR) 1996-07-24 EP claimed
US-5360529-A Reference half-cell electrode EASTMAN KODAK COMPANY (US) 1994-11-01 US claimed
US-5358653-A Continuous organic solid phase of low foaming polyoxyalkylene surfactant, encapsulate layer and core of active chlorine compound ECOLAB, INC. (US) 1994-10-25 US claimed
US-5340589-A Antiandrogenic steroids STERLING WINTHROP INC. (US) 1994-08-23 US claimed
EP-0554427-A1 REFERENCE HALF-CELL ELECTRODE. KODAK PATHE (FR) 1993-08-11 EP claimed
WO-1993004360-A1 REFERENCE HALF-CELL ELECTRODE KODAK LIMITED (GB) 1993-03-04 WO claimed
EP-0514967-A1 Low solubility drug-coated bead compositions STERLING WINTHROP INC. (US) 1992-11-25 EP claimed
US-4387092-A Process for the preparation of factor VIII concentrate SOCIETE ANONYME DITE: L'OREAL (FR) 1983-06-07 US claimed