Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.34 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231679 | 0.83 | L3MBTL1 (0.37) | TP53GAATSHRMAPTCACNA1B | |
| SCHEMBL12496757 | 0.76 | PDE7A (0.45) | TP53GAASLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL7769009 | 0.74 | GAA (0.42) | TP53GAAMAPTUSP2MAPK1 | |
| SCHEMBL8905942 | 0.73 | GAA (0.42) | TP53GAATSHRAGTR1MAPT | |
| SCHEMBL4512633 | 0.72 | GAA (0.46) | TP53GAAMAPTUSP2MAPK1 | |
| SCHEMBL7781016 | 0.71 | DDB1 (0.36) | LMNAKMT2AALDH1A1HTTL3MBTL1 | |
| SCHEMBL5929376 | 0.70 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL2759714 | 0.70 | GAA (0.39) | TP53GAATSHRAGTR1MAPT | |
| SCHEMBL14587466 | 0.69 | GAA (0.43) | TP53GAAMAPTUSP2MAPK1 | |
| SCHEMBL2969282 | 0.68 | MTOR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6256307-A | — | — | None | — | — | JP | disclosed |
| EP-0613885-B1 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-5567671-A | HERBICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-22 | — | — | US | disclosed |
| JP-H06256307-A | SUBSTITUTED 1-H-3-PHENYL-5-CYCLOALKYLPYRROLIDINE-2,4-DIONE, ITS PREPARATION AND ITS USE | BAYER AG | 1994-09-13 | — | — | JP | disclosed |
| EP-0613885-A2 | Subsituted 1-H-3-phenyl-5-cycloalkyl-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |