Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 1.00 |
| ▸ | MTNR1B | P49286 | 7/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 4/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.74 |
| ▸ | BLM | P54132 | 3/20 | 0.74 |
| ▸ | SPR | P35270 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.74 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | IDO1 | P14902 | 1/20 | 0.74 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.74 |
| ▸ | MPO | P05164 | 7/20 | 0.69 |
| ▸ | NQO2 | P16083 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HTR2B | P41595 | 2/20 | 0.69 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4488812 | 0.89 | MTNR1A (0.81) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| SCHEMBL20242784 | 0.88 | NOTUM (0.78) | MTNR1AMTNR1BNOTUMSPRMPO | |
| SCHEMBL2410324 | 0.87 | NOTUM (0.77) | MTNR1AMTNR1BNOTUMSPRMPO | |
| SCHEMBL1771902 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| SCHEMBL31543697 | 0.85 | MTNR1A (1.00) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| Acetylserotonin SCHEMBL30295379 | 0.85 | SPR (1.00) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| Acetylserotonin SCHEMBL29375184 | 0.85 | SPR (1.00) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| Acetylserotonin SCHEMBL422165 | 0.85 | SPR (1.00) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| SCHEMBL14077525 | 0.84 | NOTUM (0.72) | MTNR1AMTNR1BNOTUMCYP1A2BLM | |
| SCHEMBL32678263 | 0.84 | NOTUM (0.77) | MTNR1AMTNR1BNOTUMSPRMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4381284-B1 | LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY | ETH ZUERICH (CH) | 2025-07-09 | — | — | EP | disclosed |
| WO-2025099444-A1 | N-Acetylserotonin (NAS) Analogues | Beckley Psytech Limited (GB) | 2025-05-15 | — | — | WO | disclosed |
| US-20240345008-A1 | LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY | ETH ZURICH (CH) | 2024-10-17 | — | — | US | disclosed |
| EP-4381284-A1 | LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY | ETH Zurich (CH) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023012203-A1 | LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY | ETH ZURICH (CH) | 2023-02-09 | — | — | WO | disclosed |
| EP-4130727-A1 | LIGAND-TARGET INTERACTION ANALYSIS BY PHOTOCHEMICALLY INDUCED DYNAMIC NUCLEAR POLARIZATION (PHOTO-CIDNP) ENHANCED NMR SPECTROSCOPY | ETH Zurich (CH) | 2023-02-08 | — | — | EP | disclosed |
| US-20190247527-A1 | 18F-Labeled Compounds for PET Imaging and Uses Thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2019-08-15 | — | — | US | disclosed |
| US-7612099-B2 | Vinylogous acid derivatives | HOFFMANN-LA ROCHE INC. (US) | 2009-11-03 | — | — | US | disclosed |
| CN-101321749-A | Novel vinylogous acid derivatives | HOFFMANN LA ROCHE (CH) | 2008-12-10 | — | — | CN | disclosed |
| EP-1957483-A1 | NOVEL VINYLOGOUS ACIDS DERIVATIVES | F.HOFFMANN-LA ROCHE AG (CH) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007063010-A1 | NOVEL VINYLOGOUS ACIDS DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2007-06-07 | — | — | WO | disclosed |
| US-20070129421-A1 | Vinylogous acid derivatives | HOFFMANN-LA ROCHE INC. | 2007-06-07 | — | — | US | disclosed |
| WO-2004085392-A1 | MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS | FAUST PHARMACEUTICALS (FR) | 2004-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247527-A1 | 18F-Labeled Compounds for PET Imaging and Uses Thereof | IDO1, IDO2, CD274 | MTNR1A 1167/4885MTNR1B 1523/4885NOTUM 2973/4885 |
| US-20070129421-A1 | Vinylogous acid derivatives | CMA1, TPSG1, TPSAB1 | MTNR1A 454/4885MTNR1B 756/4885NOTUM 601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.