Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 10/20 | 0.59 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7366692 | 0.86 | GPR119 (0.59) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4701304 | 0.86 | DRD2 (0.49) | GPR119HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL13757755 | 0.85 | GPR119 (0.58) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4504053 | 0.84 | GPR119 (0.60) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4513931 | 0.84 | GPR119 (0.61) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4515782 | 0.83 | GPR119 (0.74) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL4509519 | 0.83 | GPR119 (0.58) | GPR119TGFBR1HTR1ADRD2HTR2A | |
| SCHEMBL4523959 | 0.83 | GPR119 (0.56) | GPR119TGFBR1ALDH1A1LMNAMAPT | |
| SCHEMBL13757744 | 0.82 | GPR119 (0.55) | GPR119TGFBR1LMNAMAPTDRD2 | |
| SCHEMBL4522460 | 0.82 | GPR119 (0.55) | GPR119TGFBR1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | GPR119 1/4885TGFBR1 834/4885ALDH1A1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.