Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.49 |
| ▸ | DRD3 | P35462 | 11/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513183 | 0.86 | GPR119 (0.59) | DRD2DRD3HTR1AHTR2AGPR119 | |
| SCHEMBL4514129 | 0.81 | DRD2 (0.58) | DRD2DRD3HPGDSHTR1A | |
| SCHEMBL4509537 | 0.80 | ALDH1A1 (0.53) | DRD2DRD3HTR1AHTR2A | |
| SCHEMBL4512476 | 0.79 | MAPT (0.60) | DRD2DRD3 | |
| SCHEMBL4513562 | 0.79 | CHRM4 (0.54) | DRD2DRD3HTR1A | |
| SCHEMBL4503964 | 0.78 | CHRNA10 (0.51) | DRD2DRD3HTR1A | |
| SCHEMBL4755524 | 0.78 | DRD2 (0.50) | DRD2DRD3HTR2A | |
| SCHEMBL4512341 | 0.78 | DRD2 (0.47) | DRD2DRD3HTR2A | |
| SCHEMBL4505113 | 0.78 | MAPT (0.55) | DRD2DRD3HPGDSHTR2A | |
| SCHEMBL4513998 | 0.75 | ALDH1A1 (0.50) | DRD2DRD3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909791-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003964-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |