SCHEMBL451335

SCHEMBL451335

O=C(CS)OCCCCO

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 6/20 0.40
NAAA Q02083 1/20 0.40
TSHR P16473 2/20 0.39
HSD17B10 Q99714 1/20 0.39
GAA P10253 1/20 0.34
RAD52 P43351 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CYP4F2 P78329 1/20 0.34
CYP4A11 Q02928 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
FAAH O00519 1/20 0.33
APP P05067 2/20 0.33
HTR2C P28335 1/20 0.32
GPR84 Q9NQS5 1/20 0.32
FFAR1 O14842 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
DGKA P23743 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28562184 0.98 NAAA (0.43) ACHENAAATSHRHSD17B10GAA
SCHEMBL11399084 0.98 NAAA (0.43) ACHENAAATSHRHSD17B10GAA
SCHEMBL7078848 0.98 NAAA (0.43) ACHENAAATSHRHSD17B10GAA
Ethylene Glycol SCHEMBL9137199 0.93 NAAA (0.41) ACHENAAATSHRHSD17B10RAD52
SCHEMBL454943 0.93
SCHEMBL60931 0.90 NAAA (0.46) ACHENAAATSHRHSD17B10RAD52
Ethylene Glycol SCHEMBL17106636 0.88 TSHR (0.40) NAAATSHRHSD17B10RAD52NPSR1
SCHEMBL97045 0.87 NAAA (0.50) ACHENAAATSHRHSD17B10RAD52
SCHEMBL96893 0.87 NAAA (0.50) ACHENAAATSHRHSD17B10RAD52
SCHEMBL11235417 0.87 NAAA (0.50) ACHENAAATSHRHSD17B10RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329991-A1 PERMANENT HAIR SHAPING COMPOSITION WELLA GERMANY GMBH (DE) 2023-10-19 US claimed
EP-4216912-A1 PERMANENT HAIR SHAPING COMPOSITION Wella Germany GmbH (DE) 2023-08-02 EP claimed
CN-116390709-A Permanent hair shaping composition 威娜德国有限责任公司 2023-07-04 CN claimed
CN-114957665-A Polyamide based on mercapto-Michael addition click reaction and synthetic method thereof 郑州大学 2022-08-30 CN claimed
WO-2022063917-A1 PERMANENT HAIR SHAPING COMPOSITION HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-03-31 WO claimed
EP-2509566-B2 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2022-03-09 EP claimed
EP-2509566-B1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2018-08-22 EP claimed
US-9554980-B2 Composition and process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2017-01-31 US claimed
EP-2515844-B1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-10-26 EP claimed
EP-2658519-B1 COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2016-07-20 EP claimed
US-20140246042-A1 Process for Permanent Shaping of Human Hair KAO GERMANY GMBH (DE) 2014-09-04 US claimed
US-8753616-B2 Process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2014-06-17 US claimed
US-8747825-B2 Process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2014-06-10 US claimed
US-20130276809-A1 COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2013-10-24 US claimed
EP-2191865-B1 Process for colouring and straightening keratin fibres KAO GERMANY GMBH (DE) 2013-10-23 EP claimed
US-20120255573-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2012-10-11 US claimed
US-20120234339-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2012-09-20 US claimed
EP-2468250-A1 Composition and process for permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2012-06-27 EP claimed
EP-2338471-A1 Process for permanent shaping human hair KPSS-Kao Professional Salon Services GmbH (DE) 2011-06-29 EP claimed
EP-2332515-A1 Process for permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2011-06-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120255573-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR POLR1C, PLOD2, SMOX ACHE 3242/4885NAAA 1433/4885TSHR 2804/4885
US-20130276809-A1 COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR DNMT1, TET3, TET1 ACHE 4188/4885NAAA 2465/4885TSHR 2555/4885
US-20140246042-A1 Process for Permanent Shaping of Human Hair POLR1C, PRKDC, PRKACG ACHE 3300/4885NAAA 1325/4885TSHR 2272/4885
US-20120234339-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR POLR1C, PRKDC, PRKACG ACHE 3300/4885NAAA 1325/4885TSHR 2272/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.