1,4-Butanediol

1,4-Butanediol

SCHEMBL451336

O=C(O)CS.OCCCCO

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 1/20 0.55
FFAR1 O14842 1/20 0.55
FFAR4 Q5NUL3 1/20 0.55
CAMK2A Q9UQM7 1/20 0.53
FOLH1 Q04609 1/20 0.41
FNTA P49354 1/20 0.41
FNTB P49356 1/20 0.41
LMNA P02545 5/20 0.37
SLC22A6 Q4U2R8 1/20 0.37
TSHR P16473 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NFKB1 P19838 1/20 0.35
PMP22 Q01453 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HSD17B10 Q99714 1/20 0.33
ACE P12821 1/20 0.33
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Butanediol SCHEMBL60932 1.00 GPR84 (0.55) GPR84FFAR1FFAR4CAMK2AFOLH1
1,4-Butanediol SCHEMBL31453278 1.00 GPR84 (0.55) GPR84FFAR1FFAR4CAMK2AFOLH1
Thioglycolic Acid SCHEMBL97046 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
1,5-Pentanediol SCHEMBL11585670 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
Thioglycolic Acid SCHEMBL11235420 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
Thioglycolic Acid SCHEMBL7078844 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
1,6-Hexanediol SCHEMBL98428 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
1,6-Hexanediol SCHEMBL11399082 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
Thioglycolic Acid SCHEMBL96894 0.97 GPR84 (0.60) GPR84FFAR1FFAR4CAMK2AFOLH1
Thioglycolic Acid SCHEMBL98408 0.93 CAMK2A (0.53) GPR84FFAR1FFAR4CAMK2AFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116970196-A Liquid crystal elastomer film with force color changing and acid color changing properties, preparation method and application thereof 北京大学 2023-10-31 CN claimed
US-20230329991-A1 PERMANENT HAIR SHAPING COMPOSITION WELLA GERMANY GMBH (DE) 2023-10-19 US claimed
EP-4216912-A1 PERMANENT HAIR SHAPING COMPOSITION Wella Germany GmbH (DE) 2023-08-02 EP claimed
CN-116390709-A Permanent hair shaping composition 威娜德国有限责任公司 2023-07-04 CN claimed
CN-114957665-A Polyamide based on mercapto-Michael addition click reaction and synthetic method thereof 郑州大学 2022-08-30 CN claimed
WO-2022063917-A1 PERMANENT HAIR SHAPING COMPOSITION HFC PRESTIGE SERVICE GERMANY GMBH (DE) 2022-03-31 WO claimed
EP-2509566-B2 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2022-03-09 EP claimed
CN-113101278-A Targeting nanoparticles with GSH and esterase tumor microenvironment dual responses and preparation method and application thereof 中山大学附属第七医院(深圳) 2021-07-13 CN claimed
EP-2509566-B1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2018-08-22 EP claimed
US-9554980-B2 Composition and process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2017-01-31 US claimed
US-20140246042-A1 Process for Permanent Shaping of Human Hair KAO GERMANY GMBH (DE) 2014-09-04 US claimed
US-8753616-B2 Process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2014-06-17 US claimed
US-8747825-B2 Process for permanent shaping of human hair KAO GERMANY GMBH (DE) 2014-06-10 US claimed
US-20130276809-A1 COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2013-10-24 US claimed
EP-2191865-B1 Process for colouring and straightening keratin fibres KAO GERMANY GMBH (DE) 2013-10-23 EP claimed
US-20120255573-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2012-10-11 US claimed
US-20120234339-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR KAO GERMANY GMBH (DE) 2012-09-20 US claimed
EP-2468250-A1 Composition and process for permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2012-06-27 EP claimed
EP-2338471-A1 Process for permanent shaping human hair KPSS-Kao Professional Salon Services GmbH (DE) 2011-06-29 EP claimed
EP-2332515-A1 Process for permanent shaping of human hair KPSS-Kao Professional Salon Services GmbH (DE) 2011-06-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120255573-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR POLR1C, PLOD2, SMOX GPR84 3349/4885FFAR1 2688/4885FFAR4 2572/4885
US-20130276809-A1 COMPOSITION AND PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR DNMT1, TET3, TET1 GPR84 3792/4885FFAR1 2057/4885FFAR4 2047/4885
US-20140246042-A1 Process for Permanent Shaping of Human Hair POLR1C, PRKDC, PRKACG GPR84 2945/4885FFAR1 2952/4885FFAR4 3083/4885
US-20120234339-A1 PROCESS FOR PERMANENT SHAPING OF HUMAN HAIR POLR1C, PRKDC, PRKACG GPR84 2945/4885FFAR1 2952/4885FFAR4 3083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.