Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513595 | 0.85 | HSD11B1 (0.46) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4510127 | 0.84 | HSD11B1 (0.47) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4527041 | 0.83 | LMNA (0.46) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4516607 | 0.83 | HSD11B1 (0.44) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4514812 | 0.82 | ALDH1A1 (0.46) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL13674559 | 0.81 | HSD11B1 (0.43) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4511944 | 0.81 | HSD11B1 (0.52) | HSD11B1ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL4513744 | 0.81 | HSD11B1 (0.43) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL4505773 | 0.81 | NPC1 (0.53) | HSD11B1ALDH1A1MEN1KMT2AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4515008 | 0.80 | HSD11B1 (0.42) | HSD11B1ALDH1A1HPGDKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |