Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.39 |
| ▸ | CETP | P11597 | 3/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | VEGFA | P15692 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4520340 | 0.97 | KCNH2 (0.40) | KCNH2SLC2A1CETPTRPM4L3MBTL1 | |
| SCHEMBL4521484 | 0.95 | SLC2A1 (0.42) | KCNH2SLC2A1CETPL3MBTL1LMNA | |
| SCHEMBL4524261 | 0.92 | SLC2A1 (0.42) | KCNH2SLC2A1CETPL3MBTL1LMNA | |
| SCHEMBL4509362 | 0.90 | SLC22A12 (0.42) | KCNH2SLC2A1TRPM4L3MBTL1LMNA | |
| SCHEMBL4519188 | 0.89 | KCNJ6 (0.39) | KCNH2SLC2A1CETPTRPM4L3MBTL1 | |
| SCHEMBL4511385 | 0.89 | L3MBTL1 (0.42) | KCNH2SLC2A1CETPL3MBTL1LMNA | |
| SCHEMBL4517583 | 0.88 | CYP3A4 (0.38) | KCNH2SLC2A1CETPTRPM4L3MBTL1 | |
| SCHEMBL4521806 | 0.87 | SLC2A1 (0.38) | KCNH2SLC2A1CETPL3MBTL1SLC22A12 | |
| SCHEMBL4519176 | 0.82 | SLC2A1 (0.41) | KCNH2SLC2A1CETPL3MBTL1LMNA | |
| SCHEMBL4517665 | 0.81 | SLC2A1 (0.40) | KCNH2SLC2A1CETPL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264425-A1 | CHEMICAL COMPOUNDS | PFIZER LIMITED | 2009-10-22 | — | — | US | disclosed |
| US-20090264425-A1 | CHEMICAL COMPOUNDS | PFIZER LIMITED | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264425-A1 | CHEMICAL COMPOUNDS | POLR2E, POLR2A, POLRMT | KCNH2 3855/4885SLC2A1 4452/4885CETP 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.