Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
| ▸ | MMP13 | P45452 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513697 | 0.84 | PTGES (0.77) | TP53MAPTPPARGDUSP1 | |
| SCHEMBL27188272 | 0.84 | PPARG (0.74) | TP53MAPTPPARGHPGDHSD17B10 | |
| SCHEMBL4503739 | 0.84 | TP53 (0.84) | TP53MAPTPPARGDUSP1HPGD | |
| SCHEMBL13576606 | 0.84 | MAPT (0.70) | TP53MAPTPPARGHPGDHSD17B10 | |
| SCHEMBL26687955 | 0.82 | TP53 (0.82) | TP53MAPTPPARGDUSP1HPGD | |
| SCHEMBL12127299 | 0.81 | PPARG (0.73) | TP53MAPTPPARGMEN1KMT2A | |
| SCHEMBL4501791 | 0.80 | TP53 (0.73) | TP53MAPTDUSP1HPGDGAA | |
| SCHEMBL2555051 | 0.80 | SMN1; SMN2 (0.68) | TP53MAPTHPGDGAAHSD17B10 | |
| SCHEMBL13576558 | 0.79 | KDM4E (0.64) | TP53MAPTDUSP1HSD17B10P2RY14 | |
| SCHEMBL24711762 | 0.78 | MAPT (0.67) | TP53MAPTHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | TP53 2523/4885MAPT 270/4885PPARG 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.