Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.49 |
| ▸ | SCD | O00767 | 4/20 | 0.49 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4502685 | 0.90 | ALDH1A1 (0.56) | ALDH1A1MRGPRX4LMNAMAPTMAPK1 | |
| SCHEMBL4504035 | 0.89 | ALDH1A1 (0.59) | ALDH1A1MRGPRX4LMNAMAPTMAPK1 | |
| SCHEMBL4506545 | 0.89 | SMN1; SMN2 (0.60) | ALDH1A1MRGPRX4LMNAMAPTMAPK1 | |
| SCHEMBL4492919 | 0.88 | ALDH1A1 (0.51) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL4509888 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL4506087 | 0.87 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL4516512 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL4499533 | 0.84 | SMN1; SMN2 (0.57) | ALDH1A1MRGPRX4LMNAMAPTMAPK1 | |
| SCHEMBL4492357 | 0.83 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL4517018 | 0.83 | SCD (0.53) | ALDH1A1LMNAMAPTMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | ALDH1A1 1311/4885MRGPRX4 1550/4885LMNA 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.