Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | TERT | O14746 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | EEF2K | O00418 | 2/20 | 0.39 |
| ▸ | EEF2 | P13639 | 2/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ITK | Q08881 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30096016 | 0.75 | NPC1 (0.45) | TERTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL452116 | 0.75 | NPC1 (0.45) | TERTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL29935401 | 0.74 | NPC1 (0.44) | TERTMEN1KMT2AKDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL16715320 | 0.72 | TERT (0.71) | TERTMEN1KMT2AKDM4ENPC1 | |
| SCHEMBL5294334 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5286124 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5810905 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5330266 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5810569 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K | |
| SCHEMBL5302247 | 0.71 | MEN1 (0.56) | CA1CA2MEN1KMT2AEEF2K |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | DUKE UNIVERSITY | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065181-A1 | METHOD OF PROVIDING NEUROPROTECTION USING SUBSTITUTED PORPHYRINS | SOD1, PYGB, PSAP | CA1 411/4885CA2 2341/4885TERT 4141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.