Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | KHK | P50053 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810815 | 0.86 | CYP3A4 (0.50) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL2435542 | 0.80 | CYP3A4 (0.56) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL28338346 | 0.77 | GPR35 (0.42) | CYP3A4ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29739381 | 0.77 | KDM4E (0.46) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL28920176 | 0.77 | CYP3A4 (0.41) | CYP3A4ALDH1A1THRBMAPTHPGD | |
| SCHEMBL1808542 | 0.77 | TRPV4 (0.43) | CYP3A4ALDH1A1THRBMAPTHPGD | |
| SCHEMBL15277639 | 0.77 | ALDH1A1 (0.41) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL14744340 | 0.77 | CYP3A4 (0.41) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL16236615 | 0.77 | KHK (0.43) | CYP3A4ALDH1A1THRBKDM4EMAPT | |
| SCHEMBL11808926 | 0.74 | ALDH1A1 (0.37) | CYP3A4ALDH1A1THRBKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298894-A1 | AMINO ACID COMPOUNDS | S1PR1, S1PR2, S1PR5 | CYP3A4 4658/4885ALDH1A1 2990/4885THRB 1341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.