Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 6/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | RBP4 | P02753 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518274 | 0.90 | KMT2A (0.52) | PHGDHRBP4TRPV1KDM4EMEN1 | |
| SCHEMBL4506541 | 0.89 | CYP1A2 (0.46) | CYP1A2CYP3A4PHGDHEPHX2TRPV1 | |
| SCHEMBL4509117 | 0.85 | MEN1 (0.53) | PHGDHRBP4TRPV1KDM4EMEN1 | |
| SCHEMBL4491951 | 0.82 | SMN1; SMN2 (0.50) | CYP1A2CYP3A4PHGDHTRPV1KDM4E | |
| SCHEMBL4516917 | 0.76 | EPHA2 (0.44) | PHGDHKDM4EMEN1KMT2AMAPT | |
| SCHEMBL4515668 | 0.75 | SCN9A (0.54) | RBP4MEN1KMT2AALDH1A1 | |
| SCHEMBL4506389 | 0.74 | MEN1 (0.45) | EPHX2KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4509367 | 0.74 | MEN1 (0.51) | PHGDHTRPV1KDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4504667 | 0.72 | EPHA2 (0.41) | PHGDHRBP4KDM4EMEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL4498992 | 0.72 | PHGDH (0.40) | CYP1A2CYP3A4PHGDHKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | CYP1A2 252/4885CYP3A4 121/4885PHGDH 1406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.