Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PHGDH | O43175 | 4/20 | 0.43 |
| ▸ | RBP4 | P02753 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4509117 | 0.95 | MEN1 (0.53) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4491951 | 0.91 | SMN1; SMN2 (0.50) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4516123 | 0.90 | CYP1A2 (0.43) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4509367 | 0.83 | MEN1 (0.51) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4506541 | 0.79 | CYP1A2 (0.46) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4516917 | 0.75 | EPHA2 (0.44) | KMT2AMEN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL4496434 | 0.73 | LOXL2 (0.46) | KMT2AMEN1MAPTSMN1; SMN2LOXL2 | |
| SCHEMBL4499618 | 0.73 | LOXL2 (0.42) | KMT2AMEN1SMN1; SMN2LOXL2RBP4 | |
| SCHEMBL4509555 | 0.73 | SCN9A (0.54) | KMT2AMEN1RBP4 | |
| SCHEMBL4506372 | 0.73 | TRPV1 (0.43) | KMT2AMEN1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | KMT2A 1109/4885MEN1 4180/4885MAPT 4022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.