Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26257067 | 0.89 | KMT2A (0.53) | HSD17B10ALDH1A1HPGDHTTRECQL | |
| SCHEMBL2035494 | 0.83 | ALDH1A1 (0.50) | NAPRTHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL18854079 | 0.82 | DHODH (0.67) | ALDH1A1HPGDMAPTKMT2ADHODH | |
| SCHEMBL21480785 | 0.81 | ALDH1A1 (0.45) | NAPRTHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL1733300 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1HPGDHTTRECQLSMN1; SMN2 | |
| SCHEMBL26257078 | 0.80 | PKM (0.46) | HSD17B10ALDH1A1HPGDHTTRECQL | |
| SCHEMBL18871131 | 0.80 | ALDH1A1 (0.46) | NAPRTHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL9380483 | 0.79 | AKR1C3 (0.50) | NAPRTHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL27296701 | 0.78 | KMT2A (0.38) | NAPRTHSD17B10ALDH1A1HPGDHTT | |
| SCHEMBL10412163 | 0.78 | ALDH1A1 (0.48) | NAPRTHSD17B10ALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108912001-B | Catalytic synthesis method of 1, 3-dicarbonyl compound | 华侨大学 | 2021-03-23 | — | — | CN | disclosed |
| US-20090298889-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 2-PYRIDONE DERIVATIVES AS EFFECTIVE COMPONENTS | SATO PHARMACEUTICAL CO., LTD. (JP) | 2009-12-03 | — | — | US | disclosed |
| EP-1897870-A1 | PHARMACEUTICAL COMPOSITION COMPRISING 2-PYRIDONE DERIVATIVE AS ACTIVE INGREDIENT | Sato Pharmaceutical Co. Ltd. (JP) | 2008-03-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298889-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING 2-PYRIDONE DERIVATIVES AS EFFECTIVE COMPONENTS | LTB4R2, LTB4R, CD4 | NAPRT 1229/4885HSD17B10 1341/4885ALDH1A1 436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.