Glycolic Acid

Glycolic Acid

SCHEMBL4516807

O=C([O-])CO.O=C([O-])CO.[Pt+2]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA4 P22748 5/20 0.50
OR51E2 Q9H255 1/20 0.44
CASP1 P29466 1/20 0.44
CA1 P00915 3/20 0.40
FFAR3 O14843 2/20 0.39
HDAC3 O15379 2/20 0.39
HDAC1 Q13547 2/20 0.39
HDAC2 Q92769 2/20 0.39
HDAC8 Q9BY41 2/20 0.39
FAHD1 Q6P587 1/20 0.36
CA2 P00918 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycolic Acid SCHEMBL14481648 0.96 CA4 (0.47) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL331529 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL991430 0.91
Glycolic Acid SCHEMBL134226 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL4555780 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL15441504 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL4522823 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL26512 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL1002389 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3
Glycolic Acid SCHEMBL21297631 0.91 CA4 (0.50) CA4OR51E2CASP1CA1FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11013730-B1 Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith THIOREDOXIN SYSTEMS AB (SE) 2021-05-25 US disclosed
US-10058542-B1 Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith THIOREDOXIN SYSTEMS AB (SE) 2018-08-28 US disclosed
US-8425880-B1 Metal-containing materials for treatment of bacterial conditions NUCRYST PHARMACEUTICALS CORP. (CA) 2013-04-23 US disclosed
US-20130095184-A1 Metal-Containing Materials for Treatment of Bacterial Conditions NUCRYST PHARMACEUTICALS CORP. (CA) 2013-04-18 US disclosed
EP-2043611-A2 METAL-CONTAINING FORMULATIONS AND METHODS OF USE Nucryst Pharmaceuticals Corp. (CA) 2009-04-08 EP disclosed
WO-2009014781-A2 METAL-CONTAINING MATERIALS FOR TREATMENT OF BACTERIAL CONDITIONS NUCRYST PHARMACEUTICALS CORP. (CA) 2009-01-29 WO disclosed
US-20080050452-A1 METAL-CONTAINING FORMULATIONS AND METHODS OF USE NUCRYST PHARMACEUTICALS 2008-02-28 US disclosed
US-20080044491-A1 METAL-CONTAINING FORMULATIONS AND METHODS OF USE NUCRYST PHARMACEUTICALS 2008-02-21 US disclosed
US-20080014247-A1 METAL-CONTAINING FORMULATIONS AND METHODS OF USE NUCRYST PHARMACEUTICALS 2008-01-17 US disclosed
US-20080014278-A1 METAL-CONTAINING FORMULATIONS AND METHODS OF USE NUCRYST PHARMACEUTICALS 2008-01-17 US disclosed
WO-2008005705-A2 METAL-CONTAINING FORMULATIONS AND METHODS OF USE NUCRYST PHARMACEUTICALS CORP. (CA) 2008-01-10 WO disclosed
EP-1483050-A1 CATALYSTS HAVING CONTROLLED (111) CRYSTAL FACE EXPOSURE Zhou, Bing (US) 2004-12-08 EP disclosed
US-6746597-B2 SEQUESTERING NOBLE METAL CATION BEFORE DEPOSITION ON CATALYST SUPPORT HYDROCARBON TECHNOLOGIES, INC. 2004-06-08 US disclosed
US-20030232721-A1 Supported noble metal nanometer catalyst particles containing controlled (111) crystal face exposure HYDROCARBON TECHNOLOGIES INC. 2003-12-18 US disclosed
WO-2003064037-A1 CATALYSTS HAVING CONTROLLED (111) CRYSTAL FACE EXPOSURE HYDROCARBON TECHNOLOGY, INC. (US) 2003-08-07 WO disclosed
EP-0390138-B1 Platinum complexes and antitumor agents containing them as an active ingredient SHIONOGI & CO (JP) 1994-01-05 EP disclosed
US-4968826-A REDUCED TOXICITY SHIONOGI & CO., LTD. (JP) 1990-11-06 US disclosed
EP-0390138-A1 Platinum complexes and antitumor agents containing them as an active ingredient SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1990-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11013730-B1 Composition comprising selenazol or thiazalone derivatives and silver and method of treatment therewith SELENOI, TST, SCLY CA4 4079/4885OR51E2 2821/4885CASP1 587/4885
US-10058542-B1 Composition comprising selenazol or thiazolone derivatives and silver and method of treatment therewith SELENOI, TST, GSS CA4 4062/4885OR51E2 1733/4885CASP1 609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.