Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14365058 | 0.89 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2EPHX2HSD11B1 | |
| SCHEMBL14365227 | 0.89 | ALDH1A1 (0.31) | ALDH1A1SMN1; SMN2EPHX2HSD11B1 | |
| SCHEMBL5132089 | 0.85 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2EPHX2LMNAROCK2 | |
| SCHEMBL4506472 | 0.84 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1MAPTKMT2A | |
| SCHEMBL4515192 | 0.83 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2ROCK2SCN9AMEN1 | |
| SCHEMBL4508244 | 0.79 | MLNR (0.34) | ALDH1A1SMN1; SMN2LMNASCN9AMEN1 | |
| SCHEMBL13674467 | 0.75 | BRD4 (0.33) | ALDH1A1SMN1; SMN2SCN9AMEN1KMT2A | |
| SCHEMBL5127854 | 0.75 | P2RX7 (0.38) | ALDH1A1SMN1; SMN2EPHX2LMNAHTT | |
| SCHEMBL4514220 | 0.75 | HSD11B1 (0.51) | ALDH1A1SMN1; SMN2EPHX2LMNAHTT | |
| SCHEMBL4507429 | 0.75 | EPHX2 (0.37) | ALDH1A1SMN1; SMN2EPHX2ROCK2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1864971-A1 | PROPHYLACTIC/THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2007-12-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264650-A1 | Prophylactic/Therapeutic Agent for Diabetes | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 51/4885SMN1; SMN2 4487/4885EPHX2 670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.