Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NAMPT | P43490 | 2/20 | 0.52 |
| ▸ | SCD5 | Q86SK9 | 3/20 | 0.52 |
| ▸ | SCD | O00767 | 3/20 | 0.52 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.49 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.49 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4506545 | 0.84 | SMN1; SMN2 (0.60) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4490664 | 0.83 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4496819 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4506087 | 0.80 | ALDH1A1 (0.68) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4504035 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4492357 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4499533 | 0.78 | SMN1; SMN2 (0.57) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4509888 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4518579 | 0.78 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAMAPK1HTT | |
| SCHEMBL4509302 | 0.77 | IDO1 (0.58) | ALDH1A1MAPTLMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325956-A1 | Aromatic amine derivative and use thereof | SCD, SCD5, SMS | ALDH1A1 1311/4885MAPT 4022/4885LMNA 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.