Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518556 | 1.00 | MAPT (0.45) | MAPTNPC1ALDH1A1HTTRAB9A | |
| SCHEMBL4518558 | 1.00 | MAPT (0.45) | MAPTNPC1ALDH1A1HTTRAB9A | |
| SCHEMBL4511872 | 0.93 | RAB9A (0.44) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL4511875 | 0.93 | RAB9A (0.44) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL4511867 | 0.93 | RAB9A (0.44) | MAPTNPC1RAB9ALMNARECQL | |
| SCHEMBL4500086 | 0.90 | LMNA (0.47) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4500088 | 0.90 | LMNA (0.47) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL4500077 | 0.90 | LMNA (0.47) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL13600825 | 0.90 | F2RL3 (0.45) | MAPTNPC1ALDH1A1HTTRAB9A | |
| SCHEMBL4512225 | 0.81 | MAPT (0.46) | MAPTNPC1ALDH1A1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638540-B2 | Benzofuran compound and medicinal composition containing the same | THE NEW INDUSTRY RESEARCH ORGANIZATION (JP) | 2009-12-29 | — | — | US | disclosed |
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | NEW INDUSTRY RESEARCH ORGANIZATION, THE (JP) | 2006-08-31 | — | — | US | disclosed |
| EP-1627873-A1 | BENZOFURAN COMPOUND AND MEDICINAL COMPOSITION CONTAINING THE SAME | The New Industry Research Organization (JP) | 2006-02-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194851-A1 | Benzofuran compound and medicinal composition containing the same | LTB4R2, LTC4S, LTB4R | MAPT 1497/4885NPC1 1377/4885ALDH1A1 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.