Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | HPGD | P15428 | 6/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | GLA | P06280 | 2/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 7/20 | 0.55 |
| ▸ | CA4 | P22748 | 7/20 | 0.55 |
| ▸ | CA7 | P43166 | 7/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA5A | P35218 | 6/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA3 | P07451 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25707817 | 0.85 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL19338224 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL19159597 | 0.79 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL6687148 | 0.76 | MAOB (0.76) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL11829416 | 0.76 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL455614 | 0.76 | ALDH1A1 (0.76) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL1366230 | 0.76 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL52650 | 0.76 | ALDH1A1 (0.81) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL1406631 | 0.75 | KDM4E (0.74) | ALDH1A1KDM4EHPGDGAAHSD17B10 | |
| SCHEMBL15661472 | 0.75 | ALDH1A1 (0.74) | ALDH1A1KDM4EHPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | NOVARTIS AG (CH) | 2009-12-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318546-A1 | Chromen-2-One Derivatives | CYP1A2, CYP4B1, CYP1B1 | ALDH1A1 330/4885KDM4E 2028/4885HPGD 2278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.