SCHEMBL52650

SCHEMBL52650

COc1ccc2cc(C(=O)c3cc4ccc(OC)cc4oc3=O)c(=O)oc2c1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.81
HPGD P15428 5/20 0.81
MAOB P27338 4/20 0.81
GAA P10253 3/20 0.81
SLC16A3 O15427 1/20 0.81
KDM4E B2RXH2 6/20 0.80
RAB9A P51151 2/20 0.80
NPC1 O15118 2/20 0.80
POLB P06746 1/20 0.80
GLA P06280 2/20 0.74
HSD17B10 Q99714 2/20 0.74
CA12 O43570 2/20 0.71
CA2 P00918 2/20 0.71
CA3 P07451 2/20 0.71
CA6 P23280 2/20 0.71
CA7 P43166 2/20 0.71
CA9 Q16790 2/20 0.71
CA14 Q9ULX7 2/20 0.71
CA4 P22748 1/20 0.71
CYP2C19 P33261 1/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2034492 0.91 ALDH1A1 (0.85) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL1366230 0.91 ALDH1A1 (0.81) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL5940585 0.89 ALDH1A1 (0.66) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL1104931 0.89 ALDH1A1 (1.00) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL203997 0.89 SLC16A3 (1.00) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL51978 0.89 ALDH1A1 (1.00) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL6836388 0.88 ALDH1A1 (0.65) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL20918170 0.88 ALDH1A1 (0.93) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL6687148 0.88 MAOB (0.76) ALDH1A1HPGDMAOBGAASLC16A3
SCHEMBL11829416 0.88 ALDH1A1 (0.76) ALDH1A1HPGDMAOBGAASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11382868-B2 Transdermal UV-curable hydrogel resin, hydrogel curing the same and cataplasm containing the same ICURE PHARMACEUTICAL INC. (KR) 2022-07-12 US claimed
US-10919909-B2 Photoinitiated reactions LINTFIELD LIMITED (GB) 2021-02-16 US claimed
US-20190211031-A1 PHOTOINITIATED REACTIONS LINTFIELD LIMITED (GB) 2019-07-11 US claimed
US-20190046463-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME ICURE PHARMACEUTICAL INC. (KR) 2019-02-14 US claimed
EP-3415141-A1 ULTRAVIOLET-HARDENING HYDROGEL RESIN AND HYDROGEL FOR TRANSDERMAL ADMINISTRATION, AND CATAPLASM AGENT CONTAINING SAME Icure Pharmaceutical Inc. (KR) 2018-12-19 EP claimed
US-20100137468-A1 DENTAL COMPOSITION BASED ON SILICONE CROSSLINKABLE BY CATION PROCESS BLUESTAR SILICONES FRANCE (FR) 2010-06-03 US claimed
US-7247660-B2 Dental composition based on silicone crosslinkable by cation process RHODIA CHIMIE (FR) 2007-07-24 US claimed
US-20070149636-A1 Dental composition based on silicone crosslinkable by cation process FRANCES JEAN-MARC 2007-06-28 US claimed
US-6747071-B1 SILICON CROSSLINKABLE AND/OR POLYMERIZABLE BY CATION PROCESS, AN INITIATOR SUCH AS ONIUM BORATE, A PHOTOSENSITIZER AND A DENTAL FILLER, DENTAL PROSTHESES OR FOR DENTAL RESTORATION. RHODIA CHIMIE (FR) 2004-06-08 US claimed
EP-0616701-B1 PHOTOCURABLE CYCLOBUTARENE COMPOSITIONS DOW CHEMICAL CO (US) 2002-02-13 EP claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
US-4147552-A Light-sensitive compositions with 3-substituted coumarin compounds as spectral sensitizers EASTMAN KODAK COMPANY (US) 1979-04-03 US claimed
EP-4743828-A1 PHOTOCURABLE AS WELL AS THERMALLY CURABLE COMPOSITIONS SUITABLE FOR LOW TEMPERATURE CURING BASF SE (DE) 2026-05-20 EP disclosed
EP-4555025-B1 PHOTOINITIATOR PACKAGE COMPRISING SPECIALISED BISACYLPHOSPHINE OXIDE PHOTOINITIATORS, FURTHER ACYLPHOSPHINE OXIDE PHOTOINITIATORS AND OPTICAL BRIGHTENER SENSITIZERS IGM GROUP B V (NL) 2026-05-13 EP disclosed
EP-3902878-B1 PHOTOINITIATORS IGM RESINS ITALIA SRL (IT) 2026-05-06 EP disclosed
EP-0332455-A2 Photosensitive material and image forming method CANON KABUSHIKI KAISHA (JP) 1989-09-13 EP disclosed
EP-0328364-A2 Photosensitive material CANON KABUSHIKI KAISHA (JP) 1989-08-16 EP disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919909-B2 Photoinitiated reactions KMO, DECR1, PPOX ALDH1A1 262/4885HPGD 237/4885MAOB 183/4885
US-20100137468-A1 DENTAL COMPOSITION BASED ON SILICONE CROSSLINKABLE BY CATION PROCESS ALG3, TAS2R42, ITGB5 ALDH1A1 3983/4885HPGD 824/4885MAOB 4030/4885
US-20190211031-A1 PHOTOINITIATED REACTIONS DOHH, PAH, DBH ALDH1A1 179/4885HPGD 704/4885MAOB 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.