Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.76 |
| ▸ | HPGD | P15428 | 5/20 | 0.76 |
| ▸ | MAOB | P27338 | 4/20 | 0.76 |
| ▸ | GAA | P10253 | 3/20 | 0.76 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.71 |
| ▸ | GLA | P06280 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | CA12 | O43570 | 4/20 | 0.67 |
| ▸ | CA2 | P00918 | 4/20 | 0.67 |
| ▸ | CA7 | P43166 | 3/20 | 0.67 |
| ▸ | CA9 | Q16790 | 3/20 | 0.67 |
| ▸ | CA3 | P07451 | 2/20 | 0.67 |
| ▸ | CA6 | P23280 | 2/20 | 0.67 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.67 |
| ▸ | CA4 | P22748 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1366230 | 0.88 | ALDH1A1 (0.81) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL52650 | 0.88 | ALDH1A1 (0.81) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL203997 | 0.87 | SLC16A3 (1.00) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL1104931 | 0.87 | ALDH1A1 (1.00) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL6687148 | 0.85 | MAOB (0.76) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL11829416 | 0.85 | ALDH1A1 (0.76) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL1366531 | 0.84 | CYP2C19 (0.78) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL6420525 | 0.84 | MAOB (0.60) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL23871953 | 0.83 | CYP2C19 (0.81) | ALDH1A1HPGDMAOBGAASLC16A3 | |
| SCHEMBL20414710 | 0.83 | ALDH1A1 (0.72) | ALDH1A1HPGDMAOBGAASLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112898278-B | Preparation and application of Sigma-2 fluorescent ligand | 广东医科大学 | 2022-05-13 | — | — | CN | claimed |
| CN-112898278-B | Preparation and application of Sigma-2 fluorescent ligand | 广东医科大学 | 2022-05-13 | — | — | CN | disclosed |
| US-9377466-B2 | Compounds and methods | MODPRO AB (SE) | 2016-06-28 | — | — | US | disclosed |
| US-20130261013-A1 | Compounds and Methods | MODPRO AB (SE) | 2013-10-03 | — | — | US | disclosed |
| EP-2613796-A2 | COMPOUNDS AND METHODS | Modpro AB (SE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032068-A2 | COMPOUNDS AND METHODS | MODPRO AB (SE) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130261013-A1 | Compounds and Methods | NOS2, NOS1, NOS3 | ALDH1A1 3022/4885HPGD 1480/4885MAOB 916/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.