Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | NPR3 | P17342 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTPRA | P18433 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11208660 | 1.00 | PPARG (0.40) | PPARGITGB1ITGA4NPR3KMT2A | |
| SCHEMBL7357707 | 0.88 | PPARG (0.36) | PPARGITGB1ITGA4NPR3KMT2A | |
| SCHEMBL29086848 | 0.86 | TRHDE (0.43) | PPARGNPR3KMT2ALMNANPC1 | |
| SCHEMBL27565355 | 0.86 | ALDH1A1 (0.32) | PPARGLMNATSHRALDH1A1ALOX15 | |
| SCHEMBL10687094 | 0.85 | ACE (0.40) | MME | |
| SCHEMBL10506297 | 0.85 | ACE (0.40) | MME | |
| SCHEMBL10687059 | 0.85 | ACE (0.40) | MME | |
| SCHEMBL8772935 | 0.84 | FPR2 (0.44) | PPARGITGB1ITGA4KMT2ANPC1 | |
| SCHEMBL8772938 | 0.84 | FPR2 (0.44) | PPARGITGB1ITGA4KMT2ANPC1 | |
| SCHEMBL4519604 | 0.83 | MME (0.36) | PPARGGPR142MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4657067-A2 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES, SUCH AS HISTAMINE | President And Fellows Of Harvard College (US) | 2025-12-03 | — | — | EP | disclosed |
| CN-117425495-A | Combination for the treatment of cancer | 赛达克斯制药股份有限公司 | 2024-01-19 | — | — | CN | disclosed |
| US-20220026420-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES SUCH AS HISTAMINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-27 | — | — | US | disclosed |
| EP-3881072-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES, SUCH AS HISTAMINE | President And Fellows Of Harvard College (US) | 2021-09-22 | — | — | EP | disclosed |
| WO-2020102660-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES, SUCH AS HISTAMINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-05-22 | — | — | WO | disclosed |
| US-4405705-A | HYDROPHILIC | TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) | 1983-09-20 | — | — | US | disclosed |