Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | FOS | P01100 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | JUN | P05412 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9856292 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL6075290 | 0.79 | ALDH1A1 (0.45) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL3720237 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL23428444 | 0.78 | ALDH1A1 (0.44) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL10635270 | 0.78 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL23160468 | 0.77 | AOC3 (0.49) | — | |
| SCHEMBL30378305 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL16003394 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL30682408 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL28131733 | 0.75 | MTNR1A (0.52) | TSHRHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | ALDH1A1 2449/4885CYP3A4 325/4885TSHR 2524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.