Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 7/20 | 0.72 |
| ▸ | AGPAT2 | O15120 | 5/20 | 0.66 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522357 | 0.92 | PTGES (0.70) | PTGESAGPAT2MAPTTP53SMN1; SMN2 | |
| SCHEMBL4518282 | 0.84 | PTGES (1.00) | PTGESAGPAT2MAPTTP53 | |
| SCHEMBL4510506 | 0.81 | PTGES (0.74) | PTGESAGPAT2MAPTTP53SMN1; SMN2 | |
| SCHEMBL4506643 | 0.81 | PTGES (0.83) | PTGESAGPAT2MAPTTP53SMN1; SMN2 | |
| SCHEMBL4498498 | 0.80 | PTGES (0.81) | PTGESAGPAT2MAPTTP53SMN1; SMN2 | |
| SCHEMBL7263285 | 0.75 | AGPAT2 (1.00) | AGPAT2MAPT | |
| SCHEMBL6124596 | 0.74 | CYP2C9 (0.67) | PTGESAGPAT2MAPTTHRB | |
| SCHEMBL4498530 | 0.74 | PTGES (1.00) | PTGESAGPAT2MAPTTP53 | |
| SCHEMBL4522223 | 0.73 | PTGES (0.82) | PTGESAGPAT2MAPTTP53THRB | |
| SCHEMBL4505504 | 0.73 | PTGES (0.78) | PTGESAGPAT2MAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2009-10-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090258917-A1 | Benzoxazoles Useful in the Treatment of Inflammation | IL4I1, EPX, IL4 | PTGES 162/4885AGPAT2 4533/4885MAPT 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.