Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4508163 | 0.88 | KMT2A (0.35) | GSK3BKCNH2 | |
| SCHEMBL8004344 | 0.88 | KMT2A (0.35) | GSK3BKCNH2 | |
| SCHEMBL4511682 | 0.87 | GSK3B (0.30) | GSK3BKCNH2 | |
| SCHEMBL8002222 | 0.86 | GSK3B (0.30) | GSK3BKCNH2 | |
| SCHEMBL4496419 | 0.85 | — | — | |
| SCHEMBL8006480 | 0.85 | — | — | |
| SCHEMBL4498328 | 0.85 | — | — | |
| SCHEMBL4498325 | 0.85 | — | — | |
| SCHEMBL4510550 | 0.85 | KMT2A (0.38) | BACE1 | |
| SCHEMBL4519060 | 0.85 | BACE1 (0.31) | BACE1GSK3BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | NOVARTIS AG (CH) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306062-A1 | 2,5-Disubstituted Piperidines | REN, AGTR1, AGTR2 | BACE1 1580/4885GSK3B 4815/4885KCNH2 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.