SCHEMBL4521682

SCHEMBL4521682

O=S(=O)(O)c1cnc(Cl)cn1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SIRT6 Q8N6T7 1/20 0.42
NAPRT Q6XQN6 1/20 0.33
KDM4E B2RXH2 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MAPT P10636 1/20 0.31
JUN P05412 1/20 0.30
NFKB1 P19838 1/20 0.30
NFKB2 Q00653 1/20 0.30
RELA Q04206 1/20 0.30
EGFR P00533 1/20 0.30
GAA P10253 1/20 0.30
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11561904 0.85 KDM4E (0.39) NAPRTKDM4ESMN1; SMN2
SCHEMBL20609889 0.79 SIRT6 (0.39) SIRT6NAPRTSMN1; SMN2MAPTPOLB
SCHEMBL20610121 0.77 CA2 (0.47) SIRT6SMN1; SMN2MAPTGAA
SCHEMBL422105 0.77 SIRT6 (0.38) SIRT6SMN1; SMN2MAPTPOLB
SCHEMBL28993826 0.76 SMN1; SMN2 (0.38) SIRT6SMN1; SMN2MAPTPOLB
SCHEMBL3387459 0.71 L3MBTL1 (0.42) KDM4EPOLB
Sulfuric Acid SCHEMBL28987143 0.71 SIRT6 (0.41) SIRT6NAPRTSMN1; SMN2MAPT
SCHEMBL933680 0.71
SCHEMBL11370935 0.70 HTT (0.49) KDM4ESMN1; SMN2MAPTGAAPOLB
Hydrochloric Acid SCHEMBL28287282 0.70 L3MBTL1 (0.41) KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10254648-B2 Radiation-sensitive resin composition, resin film, and electronic device ZEON CORPORTION (JP) 2019-04-09 US disclosed
US-20160209744-A1 RADIATION-SENSITIVE RESIN COMPOSITION, RESIN FILM, AND ELECTRONIC DEVICE ZEON CORPORATION (JP) 2016-07-21 US disclosed
US-20090202793-A1 Photosensitive, Aqueous Alkaline Solution-Soluble Polyimide Resin and Photosensitive Resin Composition Containing the same NIPPON KAYAKU KABUSHIKI KAISHA 2009-08-13 US disclosed
CN-1235089-C Photosensitive lithographic printing plate FUJI PHOTO FILM CO LTD (JP) 2006-01-04 CN disclosed