Sugi Predict

Sugi Predict / Compounds / Biphenyl

Biphenyl

Biphenyl

SCHEMBL4521706

Cc1ccc(OS(=O)(=O)C(F)(F)F)cc1.I.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.49

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Biphenyl. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA2 P00918 6/20 0.49
▸ CA1 P00915 4/20 0.49
▸ CA9 Q16790 4/20 0.49
▸ PPARG P37231 1/20 0.47
▸ HTT P42858 1/20 0.45
▸ SMN1; SMN2 Q16637 1/20 0.45
▸ CXCR2 P25025 2/20 0.41
▸ PTGS2 P35354 1/20 0.40
▸ CXCR1 P25024 1/20 0.40
▸ KIF11 P52732 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.39
▸ CA12 O43570 3/20 0.39
▸ CYP1A2 P05177 1/20 0.39
▸ CYP3A4 P08684 1/20 0.39
▸ CYP2C9 P11712 1/20 0.39
▸ CYP2C19 P33261 1/20 0.39
▸ FFAR1 O14842 1/20 0.39
▸ PTPN5 P54829 1/20 0.39
▸ ADORA2A P29274 1/20 0.38
▸ ADORA1 P30542 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL114434 0.98 CA2 (0.50) CA2CA1CA9PPARGHTT
Biphenyl SCHEMBL709602 0.97 CA2 (0.49) CA2CA1CA9PPARGHTT
SCHEMBL2750188 0.89 CA2 (0.57) CA2CA1CA9PPARGHTT
SCHEMBL24360466 0.87 CA2 (0.62) CA2CA1CA9CXCR2CXCR1
Hydrogen Sulfide SCHEMBL6248782 0.87 CA2 (0.55) CA2CA1CA9PPARGHTT
SCHEMBL5532552 0.87 CA2 (0.62) CA2CA1CA9CXCR2CXCR1
Biphenyl SCHEMBL4512202 0.86 BACE1 (0.51) CA2CA1CA9PPARGHTT
Toluene SCHEMBL28787236 0.85 CA1 (0.47) CA2CA1CA9PPARGHTT
Biphenyl SCHEMBL28551760 0.85 CA1 (0.53) CA2CA1CA9PPARGCXCR2
Biphenyl SCHEMBL115843 0.84 BACE1 (0.53) CA2CA1CA9PPARGHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7598018-B1 Photosensitive polymeric material for worm optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-10-06 — — US claimed
US-7291442-B1 Photosensitive polymeric material for WORM optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2007-11-06 — — US claimed
US-7001708-B1 Photosensitive polymeric material for worm optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2006-02-21 — — US claimed
US-7611823-B1 Photosensitive polymeric material for WORM optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-11-03 — — US disclosed
US-7524611-B2 Photosensitive polymeric material for worm optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-04-28 — — US disclosed
US-20080187862-A1 New photosensitive polymeric material for worm optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION INC. 2008-08-07 — — US disclosed
US-7001708-B1 Photosensitive polymeric material for worm optical data storage with two-photon fluorescent readout UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) 2006-02-21 — — US disclosed