Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | CASP9 | P55211 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 2/20 | 0.33 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4355670 | 0.96 | TRPV4 (0.38) | TRPV4CA1CA2CA7MAPT | |
| Trifluoroacetic Acid SCHEMBL4538218 | 0.90 | TGM2 (0.34) | CACNA1BGPR119F13A1TGM2TGM1 | |
| Trifluoroacetic Acid SCHEMBL4531639 | 0.89 | GPR119 (0.34) | GPR119F13A1TGM2TGM1TRPC3 | |
| SCHEMBL4355151 | 0.86 | TGM2 (0.36) | CA1CA2CA7MAPTF13A1 | |
| SCHEMBL4359263 | 0.85 | TGM2 (0.35) | GPR119F13A1TGM2TGM1TRPC3 | |
| SCHEMBL4539175 | 0.82 | F13A1 (0.43) | TRPV4CA1CA2CA7MAPT | |
| Trifluoroacetic Acid SCHEMBL4531900 | 0.82 | GPR119 (0.35) | CACNA1BGPR119F13A1TGM2TGM1 | |
| SCHEMBL4533901 | 0.81 | SMN1; SMN2 (0.39) | MEN1KMT2ANPSR1GPR119F13A1 | |
| SCHEMBL4350023 | 0.81 | SMN1; SMN2 (0.40) | CA1CA2CA7MEN1KMT2A | |
| SCHEMBL4526460 | 0.80 | SMN1; SMN2 (0.43) | MEN1KMT2ANPSR1F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |