Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 4/20 | 0.43 |
| ▸ | TGM2 | P21980 | 4/20 | 0.43 |
| ▸ | TGM1 | P22735 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347882 | 0.85 | EPHX2 (0.44) | KMT2AALDH1A1EPHX2NAMPTPOLB | |
| SCHEMBL4355670 | 0.85 | TRPV4 (0.38) | F13A1TGM2TGM1CA1CA2 | |
| SCHEMBL4526460 | 0.84 | SMN1; SMN2 (0.43) | F13A1TGM2TGM1KMT2AMEN1 | |
| Trifluoroacetic Acid SCHEMBL4521875 | 0.82 | TRPV4 (0.40) | F13A1TGM2TGM1CA1CA2 | |
| SCHEMBL4351624 | 0.81 | ENPP2 (0.44) | F13A1TGM2TGM1KMT2AMEN1 | |
| SCHEMBL4533655 | 0.79 | SMN1; SMN2 (0.47) | KMT2AMEN1NPSR1MAPT | |
| SCHEMBL4355143 | 0.77 | GPR119 (0.46) | KMT2AMEN1NPSR1 | |
| SCHEMBL4347881 | 0.77 | GPR119 (0.42) | F13A1TGM2TGM1 | |
| SCHEMBL4536272 | 0.76 | KMT2A (0.43) | TGM2KMT2AMEN1NPSR1 | |
| SCHEMBL4533901 | 0.76 | SMN1; SMN2 (0.39) | F13A1TGM2TGM1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |