SCHEMBL4522202

SCHEMBL4522202

CC1(c2ccc(Cl)cc2)Cc2ccccc2C(c2cnc3ccccc3c2)=N1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR2F2 P24468 1/20 0.38
CNR1 P21554 2/20 0.38
CNR2 P34972 2/20 0.38
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
TDP2 O95551 1/20 0.36
PDGFRB P09619 3/20 0.36
PDGFRA P16234 3/20 0.36
BRD4 O60885 2/20 0.35
CREBBP Q92793 2/20 0.35
BACE1 P56817 1/20 0.35
CYP2A6 P11509 1/20 0.34
NISCH Q9Y2I1 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
BIRC5 O15392 1/20 0.34
MAPT P10636 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29919748 1.00 NR2F2 (0.38) NR2F2CNR1CNR2AKR1C3AKR1C2
SCHEMBL4526857 0.91 NR2F2 (0.41) NR2F2AKR1C3AKR1C2TDP2PDGFRB
SCHEMBL29919746 0.91 NR2F2 (0.41) NR2F2AKR1C3AKR1C2TDP2PDGFRB
SCHEMBL29919667 0.89 NPC1 (0.42) NR2F2CNR1CNR2AKR1C3AKR1C2
SCHEMBL4410461 0.89 NPC1 (0.42) NR2F2CNR1CNR2AKR1C3AKR1C2
SCHEMBL4515249 0.88 PDGFRB (0.48) NR2F2AKR1C3AKR1C2TDP2PDGFRB
SCHEMBL4515128 0.84 CYP2A6 (0.47) NR2F2AKR1C3AKR1C2TDP2PDGFRB
SCHEMBL4517215 0.83 CNR1 (0.36) NR2F2CNR1CNR2AKR1C3AKR1C2
SCHEMBL4522982 0.81 LMNA (0.50) NR2F2AKR1C3AKR1C2TDP2PDGFRB
SCHEMBL4521615 0.79 NR2F2 (0.40) NR2F2AKR1C3AKR1C2TDP2PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230111656-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF SOYBEAN PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2023-04-13 US claimed
EP-4117436-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA Syngenta Crop Protection AG (CH) 2023-01-18 EP claimed
CN-115297727-A Method for controlling or preventing plant infection by phytopathogen microorganism corynebacterium polyspora 先正达农作物保护股份公司 2022-11-04 CN claimed
WO-2021180974-A1 METHODS OF CONTROLLING OR PREVENTING INFESTATION OF PLANTS BY THE PHYTOPATHOGENIC MICROORGANISM CORYNESPORA CASSIICOLA SYNGENTA CROP PROTECTION AG (CH) 2021-09-16 WO claimed
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME MITSUI CHEMICALS AGRO, INC. (JP) 2017-04-06 US claimed
EP-3150069-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME Mitsui Chemicals Agro, Inc. (JP) 2017-04-05 EP claimed
EP-1736471-B1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES MITSUI CHEMICALS AGRO INC (JP) 2014-01-08 EP claimed
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS AGRO, INC. (JP) 2012-11-08 US claimed
EP-2517562-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES BY APPLYING THE COMPOSITION Mitsui Chemicals Agro, Inc. (JP) 2012-10-31 EP claimed
CN-102665414-A Plant disease control composition and method for controlling plant disease using same MITSUI CHEMICALS AGRO INC 2012-09-12 CN claimed
US-7632783-B2 fungicides, pesticides for protecting rice crop, tomatoes, cucumbers and green beans; 3-(5-fluoro-3,3-dimethyl-3,4-dihydroisoquinolin-1-yl)quinoline MITSUI CHEMICALS AGRO, INC. (JP) 2009-12-15 US claimed
CN-100556904-C 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds SANKYO AGRO CO LTD (JP) 2009-11-04 CN claimed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US claimed
CN-1910172-A 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds SANKYO AGRO CO LTD (JP) 2007-02-07 CN claimed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP claimed
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2025-05-27 US disclosed
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2024-02-29 US disclosed
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2008-11-06 US disclosed
CN-1910172-A 3- (dihydro (tetrahydro) isoquinolin-1-yl) quinoline compounds SANKYO AGRO CO LTD (JP) 2007-02-07 CN disclosed
EP-1736471-A1 3-(DIHYDRO(TETRAHYDRO)ISOQUINOLIN-1-YL)QUINOLINES Sankyo Agro Company, Limited (JP) 2006-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170094971-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLICATION OF SAME BROX, HAX1, CHRM1 NR2F2 3620/4885CNR1 2178/4885CNR2 2561/4885
US-20240065267-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, HAX1, BROX NR2F2 2633/4885CNR1 2087/4885CNR2 2637/4885
US-12310365-B2 Plant disease control composition and method for controlling plant disease by applying the same SNX1, HAX1, BROX NR2F2 2633/4885CNR1 2087/4885CNR2 2637/4885
US-20080275242-A1 3-(Dihydro(Tetrahydro)Isoquinolin-1-Yl)Quinoline Compound QTRT1, RABL3, RECQL NR2F2 2146/4885CNR1 1548/4885CNR2 3088/4885
US-20120282349-A1 PLANT DISEASE CONTROL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASE BY APPLYING THE SAME SNX1, BROX, HAX1 NR2F2 2512/4885CNR1 1727/4885CNR2 2268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.