Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | AOC2 | O75106 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | SCN4A | P35499 | 2/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14416654 | 0.79 | MEN1 (0.35) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL257293 | 0.79 | HSD11B1 (0.44) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9097944 | 0.78 | LMNA (0.42) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL14547573 | 0.77 | TSHR (0.42) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL21497369 | 0.77 | TSHR (0.42) | TSHRMEN1KMT2ANPC1RAB9A | |
| Ammonia Solution, Strong SCHEMBL28719936 | 0.77 | HSD11B1 (0.42) | TSHRMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9231619 | 0.76 | ALDH1A1 (0.44) | MEN1KMT2ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL8439300 | 0.76 | — | — | |
| SCHEMBL1400220 | 0.76 | HTR7 (0.38) | NPC1RAB9ASMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL3480421 | 0.76 | PPARD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101516817-A | Process for the preparation of trifluoroethoxytoluenes | GRINDEKS JSC (LV) | 2009-08-26 | — | — | CN | disclosed |
| EP-2079674-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES | Grindeks, a joint stock company (LV) | 2009-07-22 | — | — | EP | disclosed |
| WO-2008055849-A1 | PROCESS FOR THE PREPARATION OF TRIFLUOROETHOXYTOLUENES | GRINDEKS, A JOINT STOCK COMPANY (LV) | 2008-05-15 | — | — | WO | disclosed |