Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | HTR6 | P50406 | 4/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.51 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3846722 | 0.98 | LMNA (0.59) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| SCHEMBL532144 | 0.93 | ALDH1A1 (0.69) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| Piperazine SCHEMBL27980528 | 0.92 | ALDH1A1 (0.67) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| Hydrochloric Acid SCHEMBL20482315 | 0.92 | KDM4E (0.67) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| SCHEMBL12826096 | 0.84 | LMNA (0.59) | LMNAALDH1A1AKR1C3GPR119MAPK1 | |
| SCHEMBL1970481 | 0.83 | LMNA (0.58) | LMNAKDM4EALDH1A1AKR1C3GPR119 | |
| SCHEMBL3485771 | 0.78 | GPR119 (0.64) | LMNAKDM4EALDH1A1HTR6AKR1C3 | |
| SCHEMBL82301 | 0.78 | ADRB1 (0.85) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| SCHEMBL31531621 | 0.78 | ALDH1A1 (0.71) | LMNAKDM4EALDH1A1HTR6ADRB1 | |
| SCHEMBL17276864 | 0.76 | ADRB1 (0.68) | LMNAKDM4EALDH1A1HTR6ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | PROSIDION LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |
| WO-2007003964-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203676-A1 | G-protein Coupled Receptor Agonists | GPR119, GCGR, GPBAR1 | LMNA 4434/4885KDM4E 4578/4885ALDH1A1 1188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.